A nurse is caring for a client who is at 35 weeks of gestation and has pre-term labor with intact membranes and no signs of infection.
The provider prescribes indomethacin to inhibit prostaglandin synthesis and suppress uterine contractions.
Which of the following laboratory tests should the nurse monitor while the client is receiving this medication?
Platelet count
Creatinine clearance
Liver function tests
Blood glucose levels
The Correct Answer is B
Creatinine clearance.
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis and suppresses uterine contractions. However, it can also cause renal failure in the fetus and the mother by reducing renal blood flow and glomerular filtration rate.
Therefore, the nurse should monitor the creatinine clearance, which is a measure of renal function, while the client is receiving this medication.
Choice A is wrong because indomethacin does not affect platelet count or coagulation.
Choice C is wrong because indomethacin does not affect liver function tests.
Choice D is wrong because indomethacin does not affect blood glucose levels.
Normal ranges for creatinine clearance are 88-128 mL/min for women and 97-137 mL/min for men. Normal ranges for platelet count are 150,000-450,000 cells/mm3.
Normal ranges for liver function tests vary depending on the specific test, but some common ones are: alanine aminotransferase (ALT) 7-55 U/L, aspartate aminotransferase (AST) 8-48 U/L, alkaline phosphatase (ALP) 45-115 U/L, total bilirubin 0.1-1.2 mg/dL.
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Related Questions
Correct Answer is C
Explanation
Magnesium sulfate is a drug that is used to prevent seizures associated with pre-eclampsia and to stop preterm labor.However, it can also cause adverse effects such as respiratory depression, which is a condition where the breathing rate becomes too slow and shallow.
Respiratory depression can be life-threatening for both the mother and the baby, so the nurse should monitor the client’s respiratory rate and oxygen saturation closely.
Choice A is wrong because magnesium sulfate can cause hypotension, not hypertension.Hypotension is low blood pressure, which can lead to dizziness, fainting, and shock.
Choice B is wrong because magnesium sulfate can cause hyporeflexia, not hyperreflexia.Hyporeflexia is a reduced or absent reflex response, which can indicate magnesium toxicity.
The nurse should check the client’s deep tendon reflexes regularly and stop the infusion if they are absent.
Choice D is wrong because magnesium sulfate can cause bradycardia, not tachycardia.
Bradycardia is a slow heart rate, which can reduce the blood flow to vital organs.
Correct Answer is C
Explanation
Corticosteroids are given to pregnant women who are at risk of preterm labor to help mature the lungs of the fetus and reduce the risk of respiratory distress syndrome and other complications.Corticosteroids also have a protective effect on the brain and reduce the risk of bleeding and cerebral palsy.
Choice A is wrong because administering intravenous fluids is not a specific intervention to address possible outcomes and complications of preterm labor.Intravenous fluids may be given to correct dehydration or electrolyte imbalance, but they do not prevent or treat preterm labor.
Choice B is wrong because administering tocolytics is an intervention to delay preterm labor, not to address possible outcomes and complications.
Tocolytics are drugs that inhibit uterine contractions and prolong pregnancy for a short period of time, usually 24 to 48 hours, to allow for the administration of corticosteroids or the transfer of the mother to a facility with neonatal intensive care.
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