A nurse is caring for a client who is at 35 weeks of gestation and has pre-term labor with intact membranes and no signs of infection.
The provider prescribes indomethacin to inhibit prostaglandin synthesis and suppress uterine contractions.
Which of the following laboratory tests should the nurse monitor while the client is receiving this medication?
Platelet count
Creatinine clearance
Liver function tests
Blood glucose levels
The Correct Answer is B
Creatinine clearance.
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis and suppresses uterine contractions. However, it can also cause renal failure in the fetus and the mother by reducing renal blood flow and glomerular filtration rate.
Therefore, the nurse should monitor the creatinine clearance, which is a measure of renal function, while the client is receiving this medication.
Choice A is wrong because indomethacin does not affect platelet count or coagulation.
Choice C is wrong because indomethacin does not affect liver function tests.
Choice D is wrong because indomethacin does not affect blood glucose levels.
Normal ranges for creatinine clearance are 88-128 mL/min for women and 97-137 mL/min for men. Normal ranges for platelet count are 150,000-450,000 cells/mm3.
Normal ranges for liver function tests vary depending on the specific test, but some common ones are: alanine aminotransferase (ALT) 7-55 U/L, aspartate aminotransferase (AST) 8-48 U/L, alkaline phosphatase (ALP) 45-115 U/L, total bilirubin 0.1-1.2 mg/dL.
Nursing Test Bank
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Related Questions
Correct Answer is B
Explanation
Blood pressure of 150/90 mmHg.This is because terbutaline can causeelevated blood pressureas a side effect.
The nurse should report this finding to the provider as it may indicate hypertension or a hypertensive crisis.
Choice A is wrong because a heart rate of 110/min is not abnormal for a person who has received terbutaline.Terbutaline can causefast or pounding heartbeatsas a common side effect.
Choice C is wrong because a blood glucose of 90 mg/dL is within the normal range of 70-130 mg/dL before meals.Terbutaline can causetransient hyperglycemia(high blood sugar) as a serious side effect, but this is not the case here.
Choice D is wrong because a temperature of 37°C (98.6°F) is normal for a human being.Terbutaline does not cause fever or hypothermia as a side effect.
Correct Answer is C
Explanation
The therapeutic effect of magnesium sulfate is to inhibit uterine contractions and prevent or delay preterm labor.
By assessing uterine activity, the nurse can evaluate if the medication is working or not.
Choice A is wrong because measuring urine output is not directly related to the therapeutic effect of magnesium sulfate, but rather to monitor for toxicity and renal function.
Choice B is wrong because checking deep tendon reflexes is also not directly related to the therapeutic effect of magnesium sulfate, but rather to monitor for neuromuscular effects and toxicity.
Choice D is wrong because monitoring blood pressure is not directly related to the therapeutic effect of magnesium sulfate, but rather to monitor for cardiovascular effects and toxicity.
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