A nurse is caring for a client who has multiple sclerosis and is experiencing progressive multifocal leukoencephalopathy (PML). Which of the following medications should the nurse recognize is associated with the development of PML?

Choice A Reason:

Obtaining a hospital bed and keeping all four siderails up, may not be the best choice. While a hospital bed with siderails may be appropriate for some individuals with Parkinson's disease who are at high risk of falls, keeping all four siderails up continuously can potentially restrict mobility and independence. It's important to balance safety with the client's comfort and ability to move independently.

Choice B Reason:

Removing all throw rugs from the home is correct. Throw rugs can be tripping hazards, especially for individuals with mobility issues or balance problems. Removing throw rugs can reduce the risk of trips and falls within the home.

Choice C Reason:

Installing handrails in the bathroom is correct. Installing handrails in the bathroom, especially near the toilet and shower, can provide additional support and stability for individuals with Parkinson's disease when performing daily activities. This can help prevent falls in a potentially slippery environment.

Choice D Reason:

Ensuring adequate lighting along walking spaces is correct. Good lighting is crucial for individuals with Parkinson's disease to see obstacles and hazards clearly. Adequate lighting along walking spaces helps improve visibility and reduces the risk of falls, especially during nighttime or low-light conditions.

Choice E Reason:

Keeping walking areas free of clutter is correct. Clutter and obstacles in walking areas increase the risk of tripping and falling, particularly for individuals with Parkinson's disease who may have difficulty with balance and coordination. Keeping walking areas clear of clutter helps create a safer environment.

Choice A Reason:

Dyspnea is not commonly seen in other chronic conditions of the aging older adult: This statement is incorrect. Dyspnea, or difficulty breathing, can occur in various chronic conditions commonly seen in aging adults, such as chronic obstructive pulmonary disease (COPD), heart failure, and pulmonary fibrosis, among others. Dyspnea can be a symptom of respiratory or cardiovascular issues and is not exclusive to asthma.

Choice B Reason:

Aging is associated with decreased sensitivity to medications: This statement is generally incorrect. Aging can affect drug metabolism and clearance, leading to changes in medication sensitivity. Older adults may have altered pharmacokinetics and pharmacodynamics, which can increase their sensitivity to certain medications, particularly those with sedative or CNS depressant effects. This increased sensitivity can potentially increase the risk of adverse drug reactions.

Choice C Reason:

Adverse reactions to medications in the aging older adult are lower: This statement is incorrect. While some physiological changes associated with aging may decrease the risk of adverse drug reactions, such as decreased renal function and altered drug metabolism, older adults are still at risk for adverse drug reactions due to factors such as polypharmacy, drug interactions, and increased sensitivity to medications.

Choice D Reason:

Physiological changes in the respiratory system can mimic the presence of airway obstruction: This statement is true. Physiological changes in the aging respiratory system, such as decreased lung elasticity, increased chest wall stiffness, and reduced respiratory muscle strength, can mimic the symptoms of airway obstruction seen in conditions like asthma or COPD. These changes can lead to decreased lung function, reduced exercise tolerance, and increased susceptibility to respiratory infections.