A nurse is caring for a client who has multiple sclerosis and is experiencing progressive multifocal leukoencephalopathy (PML). Which of the following medications should the nurse recognize is associated with the development of PML?

Choice A Reason:

Drooling is inappropriate. Drooling, also known as sialorrhea, is a common symptom in Parkinson's disease due to impaired swallowing and reduced control of the muscles involved in saliva production. Anticholinergic medications can exacerbate dry mouth, which may contribute to drooling. However, drooling is not typically a side effect that would be specifically associated with anticholinergic use.

Choice B Reason:

Anhidrosis is appropriate. Anhidrosis refers to the inability to sweat normally. Anticholinergic medications can inhibit sweating by blocking the action of acetylcholine on sweat glands, leading to decreased sweating and potentially causing hyperthermia. Anhidrosis is a potential side effect of anticholinergic agents and should be reported to the healthcare provider due to the risk of overheating.

Choice C Reason:

Tremors is inappropriate. Tremors are a common symptom of Parkinson's disease and are typically not caused by anticholinergic medications. In fact, anticholinergic agents are often prescribed to help reduce tremors in individuals with Parkinson's disease. Tremors would not be considered an adverse effect that the client should report in the context of anticholinergic therapy.

Choice D Reason:

Rigidity is inappropriate. Rigidity, or stiffness of the muscles, is a characteristic symptom of Parkinson's disease resulting from the loss of dopamine-producing neurons in the brain. While anticholinergic medications can help alleviate some symptoms of Parkinson's disease, they are not typically associated with rigidity. Rigidity would not be considered an adverse effect that the client should report in the context of anticholinergic therapy.

Choice A Reason:

Air cannot pass freely into the thoracic cavity through a chest wound is incorrect because air can indeed pass freely into the thoracic cavity through the chest wound in an open pneumothorax.

Choice B Reason:

The air is trapped when it enters the cavity is incorrect because the characteristic feature of an open pneumothorax is that air is not trapped; rather, it enters the thoracic cavity with each inhalation and exits with each exhalation through the chest wound.

Choice C Reason:

Air moves in and out of a wound in the chest wall is correct. In an open pneumothorax, also known as a "sucking chest wound," air can freely move in and out of the thoracic cavity through a wound in the chest wall. This occurs due to the creation of a communication pathway between the external environment and the pleural space, typically caused by a penetrating injury to the chest.

Choice D Reason:

There are no audible sounds in an open pneumothorax is incorrect because in an open pneumothorax, there may be audible sounds associated with the movement of air in and out of the wound, such as a sucking or bubbling sound, depending on the size and location of the wound. These sounds can be clinically significant and aid in the diagnosis of an open pneumothorax.