A nurse is caring for a client who has multiple sclerosis and is experiencing progressive multifocal leukoencephalopathy (PML). Which of the following medications should the nurse recognize is associated with the development of PML?
Pregabalin
Natalizumab
Furosemide
Metoprolol
The Correct Answer is B
Choice A Reason:
Pregabalin is incorrect. Pregabalin is a medication used to treat neuropathic pain, seizures, and generalized anxiety disorder. It is not associated with an increased risk of PML.
Choice B Reason:
Natalizumab is correct.: Natalizumab is a monoclonal antibody used to treat relapsing forms of MS. It is associated with an increased risk of developing PML, particularly in individuals who are JC virus antibody positive. Regular monitoring of JC virus antibody status and clinical vigilance is required when using natalizumab to reduce the risk of PML.
Choice C Reason:
Furosemide: Furosemide is a loop diuretic used to treat edema and hypertension. It is not associated with an increased risk of PML.
Choice D Reason:
Metoprolol is incorrect .Metoprolol is a beta-blocker used to treat hypertension, angina, and heart failure. It is not associated with an increased risk of PML.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A Reason:
Nutritional therapy is not appropriate. While nutritional therapy may be involved in assessing the client's overall nutritional status and dietary needs, it may not specifically address the swallowing difficulty associated with Parkinson's disease.
Choice B Reason:
Speech therapy is appropriate. Speech therapy, also known as speech-language pathology, plays a crucial role in assessing and managing dysphagia. Speech therapists can evaluate the client's swallowing function and provide interventions to improve swallowing safety and efficiency.
Choice C Reason:
Occupational therapy is incorrect. Occupational therapy focuses on helping individuals engage in meaningful activities of daily living. While occupational therapists may play a role in dysphagia management, speech therapy is typically the primary discipline involved in addressing swallowing difficulties.
Choice D Reason:
Respiratory therapy: Respiratory therapy primarily focuses on evaluating and managing respiratory conditions, such as asthma, chronic obstructive pulmonary disease (COPD), and ventilator support. While dysphagia can sometimes lead to aspiration pneumonia and respiratory complications, respiratory therapists are not typically involved in the assessment and management of dysphagia itself.
Correct Answer is D
Explanation
Choice A Reason:
Depression is incorrect. While depression can contribute to headaches in some individuals, it is more commonly associated with migraine headaches rather than tension-type headaches or cluster headaches. People with depression may experience changes in neurotransmitter levels and alterations in pain perception, which can exacerbate migraines. However, tension-type headaches and cluster headaches are generally less strongly associated with depression as a precipitating factor compared to migraines.
Choice B Reason:
Smoking is incorrect. Smoking can be a trigger for headaches in some individuals, particularly migraines, due to the vasoconstrictive effects of nicotine and other compounds in tobacco smoke. However, smoking is not universally recognized as a common precipitating factor for tension-type headaches or cluster headaches. While individuals with cluster headaches may have higher rates of smoking compared to the general population, it is not a factor commonly shared with tension-type headaches.
Choice C Reason:
Poor posture is incorrect. Poor posture can contribute to muscle tension and cervical spine strain, which may trigger tension-type headaches. However, poor posture is not typically considered a precipitating factor specific to cluster headaches. While tension-type headaches may be exacerbated by poor posture, cluster headaches are characterized by severe, unilateral pain typically centered around the eye or temple, with associated autonomic symptoms such as tearing, nasal congestion, or ptosis.
Choice D Reason:
Stress is correct. Stress is a well-established precipitating factor for both tension-type headaches and cluster headaches. Stress can lead to muscle tension and contraction, which are common triggers for tension-type headaches. Additionally, stress can also contribute to the onset or worsening of cluster headaches, although the exact mechanisms underlying this association are not fully understood. Therefore, stress is a common precipitating factor for both tension-type headaches and cluster headaches.

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