A nurse is caring for a client who has an infection and a prescription for gentamicin Intermittent IV bolus every 8 hr. A peak and trough are required with the next dose. Which of the following actions should the nurse take to obtain an accurate gentamicin serum level?

Draw a peak level 90 min prior to administering the medication and a trough level 90 min after the dose.

Draw a trough level immediately prior to administering the medication and a peak level 30 min after the

dose.

Draw a trough level at 0900 and a peak level at 2100.

Answer and Explanation

The Correct Answer is B

To obtain an accurate gentamicin serum level, the nurse should draw a trough level immediately before administering the next dose of medication and a peak level 30 minutes after the dose has been administered. The trough level measures the lowest concentration of the medication in the blood, while the peak level measures the highest concentration.

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Correct Answer is C

Explanation

Vancomycin is a glycopeptide antibiotic that is eﬀective against gram-positive bacteria, particularly against MRSA, which is resistant to other antibiotics like methicillin. It is not eﬀective against gram-negative bacteria such as Pseudomonas aeruginosa and Klebsiella. Candida is a fungal infection and is not treated with vancomycin. Therefore, in this educational program, the nurse manager should emphasize that vancomycin is indicated for the treatment of infections caused by MRSA.

A. Grapefruit juke B. Pepperoni C. Smoked salmon D. Orange juice

Correct Answer is A

Explanation

Cyclosporine is an immunosuppressant medication that is often used following organ transplant to prevent rejection. Grapefruit juice can increase the absorption of cyclosporine, leading to an increased risk of side eﬀects and toxicity. Therefore, clients taking cyclosporine should be advised to avoid grapefruit and grapefruit juice while taking this medication. Pepperoni and smoked salmon do not have any known interactions with cyclosporine. Orange juice may also interact with cyclosporine, but not to the same extent as grapefruit juice. It is generally recommended that clients taking cyclosporine avoid drinking large amounts of orange juice and to inform their healthcare provider if they experience any adverse eﬀects.

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A nurse is caring for a client who has an infection and a prescription for gentamicin Intermittent IV bolus every 8 hr. A peak and trough are required with the next dose. Which of the following actions should the nurse take to obtain an accurate gentamicin serum level?

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