A nurse in a provider's office is assessing a client who has hypothyroidism and has been taking levothyroxine for 2 months.
Which of the following statements by the client indicates a therapeutic response to the medication?
"I am taking a laxative for constipation”
"I have noticed I'm not as cold as I use to be”
"I am losing weight without dieting”
"I seem to be sleeping more than usual”
The Correct Answer is B
Levothyroxine is a thyroid hormone medicine used to treat hypothyroidism (low thyroid hormone)1.
It works by replacing thyroid hormone that is normally produced by the body.
Cold intolerance is a common symptom of hypothyroidism2, so if the client reports that they are not as cold as they used to be, it indicates that the medication is working and their hormone levels are returning to a healthy range.
Choice A is wrong because constipation is a common symptom of hypothyroidism2, so taking a laxative for constipation does not indicate a therapeutic response to the medication.
Choice C is wrong because weight loss without dieting can be a side effect of taking too much levothyroxine.
Choice D is wrong because sleeping more than usual can be a symptom of hypothyroidism2, so it does not indicate a therapeutic response to the medication.
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Naxlex Comprehensive Predictor Exams
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Correct Answer is C
Explanation
Using sildenafil together with nitroglycerin is not recommended.

Combining these medications may cause blood pressure to fall excessively, which can lead to cardiovascular collapse.
Choice A is wrong because Albuterol, is not a contraindication for receiving sildenafil.
Choice B is wrong because Indomethacin, is not a contraindication for receiving sildenafil.
Choice D is wrong because Furosemide, is not a contraindication for receiving sildenafil.
Correct Answer is A
Explanation
Choice A rationale: Administering filgrastim after chemotherapy is a standard practice to boost white blood cell count. However, filgrastim should not be given within 24 hours before or after chemotherapy, as it can affect the efficacy and increase the risk of side effects. Administering the medication 12 hours after chemotherapy falls within this contraindicated window, necessitating an incident report.
Choice B rationale: Filgrastim can be stored at room temperature for short periods, and 2 hours is generally within acceptable limits for stability.
Choice C rationale: An absolute neutrophil count of 2,500/mm³ is within the normal range, and there is no contraindication for administering filgrastim.
Choice D rationale: Flushing the client's IV line with dextrose 5% in water before and after administering filgrastim is not appropriate, as this medication is typically administered with saline solution. Using an incorrect flushing solution could affect the medication's efficacy or compatibility, necessitating an incident report.
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