A client is newly prescribed a medication that will block the effects of histamine for the treatment of a mental health disorder. The client asks, “What side effects should I anticipate with this new medication?” Which response by the nurse is accurate?

“You should expect weight loss.”

“You should expect to feel drowsy.”

“You should expect to experience insomnia.”

“You should expect your blood pressure to increase.”

Answer and Explanation

The Correct Answer is B

Choice A reason: Histamine blockade, as in antipsychotics like olanzapine, promotes sedation, not weight loss. Weight gain is common due to histamine’s role in appetite regulation via hypothalamic signaling. Weight loss is not a typical side effect, making this response inaccurate for histamine-blocking medications.

Choice B reason: Histamine receptor blockade, common in medications like quetiapine, reduces wakefulness by inhibiting histamine’s alerting effects in the cortex. This causes drowsiness, a frequent side effect in psychiatric treatments, aligning with the pharmacological mechanism and making this the correct response.

Choice C reason: Insomnia is not typical with histamine blockade, which promotes sedation. Histamine enhances alertness; blocking it, as in antihistaminic antipsychotics, induces sleepiness, not wakefulness. This response contradicts the neuropharmacological effect, making it incorrect for expected side effects.

Choice D reason: Blood pressure increase is unrelated to histamine blockade. Histamine affects wakefulness and appetite, not vascular tone directly. Antihistaminic drugs may cause orthostatic hypotension via other receptors, not hypertension, making this response inaccurate for histamine-blocking medication effects.

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Correct Answer is B

Explanation

Choice A reason: Arising slowly addresses orthostatic hypotension, a side effect of alpha-1 receptor blockade, not dopamine effects. First-generation antipsychotics primarily block D2 receptors, affecting motor and cognitive pathways, not vascular tone. Hypotension is unrelated to dopaminergic effects, making this teaching point scientifically inaccurate.

Choice B reason: Dopamine D2 receptor blockade in the nigrostriatal pathway causes extrapyramidal symptoms, like muscle stiffness, in first-generation antipsychotics. This mimics Parkinson’s disease due to reduced dopamine signaling, impairing motor control. Teaching patients to report stiffness ensures early detection and management, aligning with the neuropharmacological impact of these drugs.

Choice C reason: Chewing sugarless gum addresses dry mouth, an anticholinergic side effect, not dopaminergic. First-generation antipsychotics block muscarinic receptors, not dopamine, causing reduced salivation. While common, this is unrelated to dopaminergic effects, making this teaching point irrelevant for the specified drug mechanism.

Choice D reason: Increasing dietary fiber addresses constipation, another anticholinergic effect, not dopaminergic. Dopamine blockade affects motor and reward systems, not gastrointestinal motility, which is regulated by muscarinic receptors. This teaching point does not correspond to the dopaminergic effects of first-generation antipsychotics, rendering it incorrect.

A. Decrease dopamine at receptor sites B. Inhibit GABA production C. Prevent destruction of acetylcholine D. Increase dopamine sensitivity

Correct Answer is C

Explanation

Choice A reason: Decreasing dopamine is used for disorders like schizophrenia, where excess mesolimbic dopamine causes hallucinations. Memory difficulties, often linked to Alzheimer’s, involve cholinergic deficits, not dopamine excess. Reducing dopamine could worsen cognition by disrupting reward and attention pathways, making this approach scientifically inappropriate for memory issues.

Choice B reason: Inhibiting GABA production is irrelevant for memory. GABA regulates neural inhibition, and its reduction could increase excitability, worsening conditions like seizures. Memory deficits, particularly in dementia, stem from reduced acetylcholine in the hippocampus, not GABA, making this option misaligned with the neurobiology of memory impairment.

Choice C reason: Preventing acetylcholine destruction, via cholinesterase inhibitors, enhances cholinergic activity in the hippocampus and cortex, critical for memory in conditions like Alzheimer’s. Low acetylcholine levels impair neural signaling, causing memory deficits. This approach directly addresses the neurochemical basis of memory difficulties, making it scientifically appropriate for treatment.

Choice D reason: Increasing dopamine sensitivity is relevant for disorders like Parkinson’s, not memory deficits. Dopamine affects motivation and movement, not memory, which relies on acetylcholine in the hippocampus. Enhancing dopamine could disrupt cognitive balance, worsening memory without addressing the cholinergic deficits central to memory impairment.

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A client is newly prescribed a medication that will block the effects of histamine for the treatment of a mental health disorder. The client asks, “What side effects should I anticipate with this new medication?” Which response by the nurse is accurate?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A patient is taking a first-generation antipsychotic medication. What should the nurse teach about the drug’s strong dopaminergic effect?

Correct Answer is B

Explanation

On the basis of current knowledge of neurotransmitter effects, a nurse anticipates that the treatment plan for a patient with memory difficulties may include medications designed to do what?

Correct Answer is C

Explanation

A patient reports experiencing performance anxiety in front of an audience. The nurse should be aware that this type of anxiety is often treated with which medication?

A client experiences panic attacks when confronted with riding in elevators. The nurse is teaching the client to use relaxation techniques while gradually exposing the client to getting on an elevator. Which technique is the nurse using?

A patient says to the nurse, “I dreamed I was pusillanimous. When I woke up, I felt emotionally drained, as though I hadn’t rested well.” Which comment would be appropriate if the nurse seeks clarification?

A nursing student says, “Little of what takes place on the behavioral health unit seems to be theory-based.” A nurse educates the student by identifying which is a common use of Sullivan’s theory on the inpatient psychiatric unit?

Your patient sometimes forgets to eat. In which part of the nursing care plan would the nurse expect to find this statement: “Offer snacks and finger foods frequently”?

A patient discloses several concerns and associated feelings. If the nurse wants to seek clarification, which comment would be appropriate?

“I’m concerned whether we are behaving ethically by restraining one patient to prevent them from self-mutilating while placing another patient on one-on-one supervision to prevent them from self-mutilating.” Which ethical principle most clearly applies to this situation?