A client is experiencing a panic attack. What medication will provide the quickest relief from acute severe anxiety symptoms?

Choice A reason: Histamine blockade, as in antipsychotics like olanzapine, promotes sedation, not weight loss. Weight gain is common due to histamine’s role in appetite regulation via hypothalamic signaling. Weight loss is not a typical side effect, making this response inaccurate for histamine-blocking medications.

Choice B reason: Histamine receptor blockade, common in medications like quetiapine, reduces wakefulness by inhibiting histamine’s alerting effects in the cortex. This causes drowsiness, a frequent side effect in psychiatric treatments, aligning with the pharmacological mechanism and making this the correct response.

Choice C reason: Insomnia is not typical with histamine blockade, which promotes sedation. Histamine enhances alertness; blocking it, as in antihistaminic antipsychotics, induces sleepiness, not wakefulness. This response contradicts the neuropharmacological effect, making it incorrect for expected side effects.

Choice D reason: Blood pressure increase is unrelated to histamine blockade. Histamine affects wakefulness and appetite, not vascular tone directly. Antihistaminic drugs may cause orthostatic hypotension via other receptors, not hypertension, making this response inaccurate for histamine-blocking medication effects.

Choice A reason: Justice ensures fair treatment across patients. Different interventions (restraint vs. supervision) for self-mutilation, possibly due to serotonin dysregulation, must be equitably applied based on clinical need, not bias. Ensuring consistent, fair application of interventions aligns with justice, addressing ethical concerns about differential treatment in psychiatric care.

Choice B reason: Autonomy involves respecting patient choices, but self-mutilation, driven by impulsivity or emotional dysregulation, requires safety interventions overriding choice. Restraint and supervision prioritize safety over autonomy, making this principle less relevant than justice, which focuses on equitable treatment across patients in this scenario.

Choice C reason: Fidelity emphasizes keeping promises or loyalty to patients, not the fairness of intervention choices. While trust is crucial, the concern here is equitable treatment for self-mutilation, not commitment to promises. Fidelity is secondary to justice in addressing differential interventions, making it incorrect.

Choice D reason: Beneficence focuses on doing good, like preventing harm in self-mutilation. Both restraint and supervision aim to protect, but the ethical concern is fairness, not benefit. Justice addresses equitable application of interventions, making beneficence less directly applicable to the ethical dilemma described.