Which statement most clearly reflects the stigma of mental illness?

Choice A reason: Serotonin acts on 5-HT receptors, not muscarinic or nicotinic subtypes. It modulates mood and behavior but lacks the receptor diversity of acetylcholine. Serotonin’s receptors are G-protein-coupled or ligand-gated, unrelated to muscarinic or nicotinic mechanisms, making it incorrect for this neurotransmitter classification.

Choice B reason: Acetylcholine binds to muscarinic (G-protein-coupled) and nicotinic (ligand-gated) receptors. Muscarinic receptors regulate parasympathetic functions like heart rate, while nicotinic receptors mediate muscle contraction and CNS signaling. This dual receptor system is unique to acetylcholine, making it the correct neurotransmitter for this question.

Choice C reason: Dopamine acts on D1 and D2 receptors, not muscarinic or nicotinic subtypes. It regulates reward and motor functions but lacks the cholinergic receptor classifications. Dopamine’s receptors are G-protein-coupled, not ligand-gated like nicotinic, making it an incorrect choice for this neurotransmitter property.

Choice D reason: GABA binds to GABA-A (ligand-gated) and GABA-B (G-protein-coupled) receptors, not muscarinic or nicotinic. It inhibits neural activity, unrelated to cholinergic systems. GABA’s receptors mediate inhibitory signaling, not the excitatory or parasympathetic functions of muscarinic/nicotinic receptors, rendering it incorrect for this question.

Choice A reason: Sullivan’s interpersonal theory emphasizes therapeutic relationships and social environments to foster mental health. The therapeutic milieu, structured to promote safety and interaction, aligns with Sullivan’s focus on interpersonal dynamics, reducing symptoms like anxiety through supportive settings, which stabilize neurotransmitter imbalances, enhancing patient recovery on psychiatric units.

Choice B reason: Sullivan’s theory does not focus on age-appropriate versus arrested behaviors. It emphasizes interpersonal relationships, not developmental stages. Assessment tools for behavior typically rely on other frameworks, like Erikson’s, which address developmental milestones, not Sullivan’s interpersonal model, making this option scientifically inaccurate for the theory’s application.

Choice C reason: Restraint and seclusion are not part of Sullivan’s theory, which promotes therapeutic relationships to reduce anxiety, not coercive measures. These interventions contradict Sullivan’s focus on supportive environments, as they may exacerbate stress and neurotransmitter dysregulation, such as increased cortisol, worsening mental health outcomes in psychiatric settings.

Choice D reason: The nursing process is a general framework, not specific to Sullivan’s theory. Sullivan’s interpersonal model focuses on relationships to alleviate symptoms, not on sequencing nursing actions. While the nursing process guides care, it is not derived from Sullivan’s principles, making this option unrelated to his theoretical application.