Which neurotransmitter has both muscarinic and nicotinic receptor subtypes?
Serotonin
Acetylcholine
Dopamine
Gamma-aminobutyric acid (GABA)
The Correct Answer is B
Choice A reason: Serotonin acts on 5-HT receptors, not muscarinic or nicotinic subtypes. It modulates mood and behavior but lacks the receptor diversity of acetylcholine. Serotonin’s receptors are G-protein-coupled or ligand-gated, unrelated to muscarinic or nicotinic mechanisms, making it incorrect for this neurotransmitter classification.
Choice B reason: Acetylcholine binds to muscarinic (G-protein-coupled) and nicotinic (ligand-gated) receptors. Muscarinic receptors regulate parasympathetic functions like heart rate, while nicotinic receptors mediate muscle contraction and CNS signaling. This dual receptor system is unique to acetylcholine, making it the correct neurotransmitter for this question.
Choice C reason: Dopamine acts on D1 and D2 receptors, not muscarinic or nicotinic subtypes. It regulates reward and motor functions but lacks the cholinergic receptor classifications. Dopamine’s receptors are G-protein-coupled, not ligand-gated like nicotinic, making it an incorrect choice for this neurotransmitter property.
Choice D reason: GABA binds to GABA-A (ligand-gated) and GABA-B (G-protein-coupled) receptors, not muscarinic or nicotinic. It inhibits neural activity, unrelated to cholinergic systems. GABA’s receptors mediate inhibitory signaling, not the excitatory or parasympathetic functions of muscarinic/nicotinic receptors, rendering it incorrect for this question.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Prolonged silences may cause withdrawal in some patients, as anxiety from serotonin or GABA imbalances can heighten discomfort. However, this does not guide silence’s use. Silence is therapeutic when timed appropriately, not avoided due to potential withdrawal, making this principle incorrect.
Choice B reason: Nurses breaking silences assumes discomfort, ignoring therapeutic benefits. Silence allows processing, potentially calming amygdala hyperactivity in anxiety. The nurse’s role is to use silence strategically, not to interrupt it routinely, making this principle misaligned with effective interview techniques.
Choice C reason: Silence facilitates reflection, allowing patients to process emotions, reducing stress via hypothalamic calming. In disorders like depression, it supports cognitive restructuring by giving time to integrate thoughts. This principle guides therapeutic silence, aligning with neurobiological benefits of reflective pauses in interviews.
Choice D reason: Silence does not inherently confirm understanding. It may allow emotional processing, but assuming it signals comprehension risks miscommunication. In conditions like anxiety, silence supports reflection, not validation, making this principle less accurate than reflection for guiding its therapeutic use.
Correct Answer is B
Explanation
Choice A reason: Active suicidality, linked to severe serotonin deficits, requires inpatient hospitalization for constant monitoring to ensure safety. Partial hospitalization is insufficient for acute risk, as it lacks 24-hour supervision, making this patient inappropriate for this less intensive care setting.
Choice B reason: Agoraphobia and panic episodes, driven by norepinephrine surges, benefit from partial hospitalization’s structured psychoeducation and therapy. Relaxation techniques reduce amygdala hyperactivity, supporting outpatient management with daily support, making this patient suitable for partial hospitalization’s intensive, non-residential treatment.
Choice C reason: Stable lithium levels indicate controlled bipolar disorder, not requiring partial hospitalization. Regular follow-up manages neurotransmitter balance, suitable for outpatient care. Partial hospitalization is for active symptoms, not stable patients, making this an incorrect referral choice.
Choice D reason: Alcohol use concerns suggest outpatient substance abuse programs, not partial hospitalization. While dopamine reward pathways are involved, partial hospitalization targets acute psychiatric symptoms, not substance issues alone, making this patient unsuitable for this level of care.
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