Which statement by a mature adult client with advanced prostate cancer best indicates that he has reached a level of acceptance of his prognosis?

To calculate the amount of darbepoetin alfa that the nurse should administer, you can use the following formula:

Dose (mL) = Amount prescribed (mcg) / Concentration (mcg/mL)

In this case:

Amount prescribed = 40 mcg
Concentration = 60 mcg/mL

Dose (mL) = 40 mcg / 60 mcg/mL = 2/3 mL

Now, you can convert 2/3 mL to decimal to make it easier to work with:

2/3 = 0.6667 mL

Rounded to one decimal place, the nurse should administer approximately 0.7 mL of darbepoetin alfa. So, the correct answer is 0.7 mL.

Choice A rationale:

The client's statement, "I should avoid foods that are high in vitamin K," indicates an understanding of the medication. Warfarin is an anticoagulant medication that works by inhibiting vitamin K-dependent clotting factors. Consistent intake of vitamin K-containing foods helps maintain a stable INR (International Normalized Ratio) and warfarin's effectiveness. Clients on warfarin should be educated about avoiding drastic changes in their vitamin K intake.

Choice B rationale:

Taking warfarin with food or on an empty stomach doesn't significantly impact its efficacy. Therefore, this statement is not indicative of the client's understanding of the medication.

Choice C rationale:

The statement "I should report any unusual bleeding or bruising to my provider" is important but doesn't specifically reflect an understanding of warfarin. It's a general caution for anyone taking anticoagulants.

Choice D rationale:

While it's important to avoid excessive use of medications like aspirin that can increase the risk of bleeding, this statement doesn't directly demonstrate an understanding of warfarin itself.