Which of the following would reduce the absorption of ciprofloxacin?
Alcohol
Intense physical exertion
Fruit juices, in particular grapefruit juice
Antacids or mineral supplements
The Correct Answer is D
A.Alcohol:
Alcohol consumption does not directly reduce the absorption of ciprofloxacin. However, alcohol can interact with certain medications and may exacerbate side effects such as dizziness, drowsiness, and gastrointestinal upset. It’s generally advisable to avoid excessive alcohol consumption while taking ciprofloxacin, but alcohol itself does not significantly affect the absorption of the medication.
B. Intense physical exertion:
Intense physical exertion is unlikely to directly reduce the absorption of ciprofloxacin. However, gastrointestinal motility may increase during intense exercise, potentially affecting the absorption of oral medications. In some cases, gastrointestinal disturbances associated with physical exertion may affect the absorption of ciprofloxacin, but this effect is generally minor and not a significant concern for most individuals.
C. Fruit juices, in particular grapefruit juice:
Grapefruit juice is known to interact with certain medications by inhibiting intestinal enzymes responsible for drug metabolism, leading to increased drug concentrations in the bloodstream. However, ciprofloxacin is not significantly affected by grapefruit juice. In fact, fruit juices, including grapefruit juice, are generally not known to reduce the absorption of ciprofloxacin.
D. Antacids or mineral supplements:
Antacids and mineral supplements containing aluminum, magnesium, calcium, or iron can significantly reduce the absorption of ciprofloxacin when taken concurrently. These substances can form complexes with ciprofloxacin in the gastrointestinal tract, reducing its bioavailability. Therefore, it’s recommended to avoid taking antacids or mineral supplements containing these minerals within a few hours before or after taking ciprofloxacin to avoid interference with its absorption.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. “It’s fine for me to become pregnant while taking this medication.”
This statement is incorrect. Tetracycline is known to have teratogenic effects, meaning it can harm the developing fetus if taken during pregnancy. Women of childbearing age should use effective contraception while taking tetracycline and avoid becoming pregnant during treatment.
B. “I will need to postpone my vacation at the beach until I finish this medication."
This statement demonstrates an understanding of the discharge instructions. Tetracycline can increase the risk of sunburn and photosensitivity reactions. Therefore, it's advisable for the client to avoid prolonged sun exposure, particularly during peak sunlight hours, and to use sun protection measures such as wearing protective clothing, using sunscreen, and avoiding tanning beds or sunlamps. Postponing a vacation at the beach until after finishing the medication is a prudent precaution to minimize the risk of sun-related side effects.
C. “I am so glad to be leaving today because I have an appointment at the tanning salon."
This statement is incorrect. Tetracycline can increase the risk of sunburn and photosensitivity reactions. Visiting a tanning salon while taking tetracycline can further increase the risk of skin damage and should be avoided.
D. "I will stop taking this medication as soon as I feel better.”
This statement is incorrect. It's important for the client to complete the full course of tetracycline as prescribed by their healthcare provider, even if they start to feel better before finishing the medication. Stopping the medication prematurely can lead to incomplete treatment and potential recurrence of the infection.
Correct Answer is A
Explanation
A. Keep the serum drug level within the therapeutic margin:
This is the correct goal of monitoring peak and trough levels during antibacterial therapy. The therapeutic margin refers to the range of drug concentrations in the bloodstream that achieves optimal therapeutic effects while avoiding toxicity. By monitoring peak and trough levels, healthcare providers can adjust the dosing regimen to maintain drug levels within this therapeutic margin.
B. Increase the therapeutic effect of the drug by gradually decreasing the drug dose:
This statement is incorrect. Monitoring peak and trough levels is not about increasing the therapeutic effect of the drug by gradually decreasing the drug dose. Instead, it's about ensuring that the drug levels are maintained within the appropriate therapeutic range to achieve optimal efficacy without causing adverse effects.
C. Provide maximum physical comfort to the patient:
Monitoring peak and trough levels is not primarily aimed at providing physical comfort to the patient. While optimizing drug therapy can contribute to improved clinical outcomes and patient well-being, the goal of monitoring these levels is specifically related to achieving therapeutic drug concentrations.
D. Treat the main disorder with no psychological distress to the patient:
This statement is unrelated to the goal of monitoring peak and trough levels during antibacterial therapy. While psychological distress may be a consideration in patient care, the primary goal of monitoring drug levels is to ensure therapeutic efficacy and safety.
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