Which of the following statements about the various forms of hepatitis is accurate?

Choice A reason: Congenital anomalies of the central nervous system are not a common complication of GDM, as they usually occur in the first trimester, before GDM develops. However, GDM can increase the risk of other congenital anomalies, such as cardiac defects or neural tube defects.

Choice B reason: Preterm birth is a possible complication of GDM, as it can be caused by maternal hypertension, preeclampsia, or placental abruption. However, it is not the most likely complication, as GDM can also delay the onset of labor and prolong the pregnancy.

Choice C reason: Low birth weight is not a typical complication of GDM, as it is more associated with intrauterine growth restriction (IUGR), which is caused by placental insufficiency. GDM can cause the opposite problem, which is excessive fetal growth.

Choice D reason: Macrosomia is the most common complication of GDM, as it is defined as a birth weight of more than 4,000 grams (8.8 pounds). It is caused by the excess glucose crossing the placenta and stimulating the fetal insulin production, which leads to increased fat deposition and organ enlargement. Macrosomia can increase the risk of birth trauma, shoulder dystocia, and neonatal hypoglycemia.

Choice A reason: None of the above is incorrect because the other choices are not true statements about the overall number of cases of STIs.

Choice B reason: Staying about the same is incorrect because the overall number of cases of STIs is not constant. According to the World Health Organization, more than 1 million STIs are acquired every day worldwide.

Choice C reason: Going down is incorrect because the overall number of cases of STIs is not decreasing. On the contrary, some STIs such as syphilis, gonorrhea, and chlamydia are resurging in many regions due to factors such as antimicrobial resistance, lack of access to prevention and treatment services, and stigma.

Choice D reason: Rising is correct because the overall number of cases of STIs is increasing globally. The World Health Organization estimates that there were 376 million new cases of four curable STIs (chlamydia, gonorrhea, syphilis, and trichomoniasis) in 2016, up from 357 million in 2012. Additionally, there are millions of cases of incurable STIs such as herpes, HPV, and HIV that affect the health and well-being of people worldwide.