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Choice A reason: Hyperbilirubinemia is incorrect because it is not a major complication of infants of diabetic mothers. It is a condition where the baby has high levels of bilirubin in the blood, which can cause jaundice. It can occur in any newborn, but it is more common in premature babies, babies with blood type incompatibility, or babies with infections.

Choice B reason: Hypoglycemia is correct because it is a major complication of infants of diabetic mothers. It is a condition where the baby has low blood sugar levels, which can cause seizures, lethargy, or poor feeding. It can occur because the baby's pancreas produces too much insulin in response to the mother's high blood sugar levels during pregnancy.

Choice C reason: Hypoinsulinemia is incorrect because it is not a major complication of infants of diabetic mothers. It is a condition where the body does not produce enough insulin, which can cause high blood sugar levels. It can occur in children or adults with type 1 diabetes, but not in newborns of diabetic mothers.

Choice D reason: Hypercalcemia is incorrect because it is not a major complication of infants of diabetic mothers. It is a condition where the baby has high levels of calcium in the blood, which can cause muscle weakness, vomiting, or kidney stones. It can occur in babies with certain genetic disorders, such as Williams syndrome, or babies with hyperparathyroidism, but not in infants of diabetic mothers.

Choice A: Decreased production of erythrocytes

This is not the primary cause of iron deficiency anemia during pregnancy. While erythrocyte production may be affected in certain conditions, it is not directly linked to iron deficiency anemia in pregnancy¹.

Choice B: Inadequate intake of iron

This is the correct answer. During pregnancy, the body needs more iron to make hemoglobin for the increased volume of blood. If the intake of iron is not sufficient, it could lead to iron deficiency anemia¹.

Choice C: Dilution of hemoglobin concentration

While it's true that the blood volume increases during pregnancy, leading to a relative dilution of hemoglobin, this is not the primary cause of iron deficiency anemia. The main issue is the lack of sufficient iron intake¹.

Choice D: The fetus establishing iron stores

While the fetus does require iron, which it gets from the mother, this is not the primary cause of iron deficiency anemia during pregnancy. The main issue is still the mother's inadequate intake of iron¹.