Which of the following describes a characteristic of cancer cells?

Maintaining specialized cell functions

Loss of contact inhibition

Ability to repair DNA damage

Orderly cell cycle progression

Answer and Explanation

The Correct Answer is B

A.   Cancer cells typically lose their specialized functions and characteristics that normal cells have. This loss of differentiation is known as dedifferentiation, where cancer cells become less specialized and more primitive in nature. This allows them to proliferate rapidly and invade surrounding tissues.
B.   Contact inhibition refers to the normal process where cells stop dividing when they come into contact with neighboring cells. In cancer cells, this mechanism is disrupted, leading to uncontrolled cell growth and proliferation. Cancer cells continue to divide and grow even when they are in close contact with other cells, which contributes to tumor formation and progression.
C.   Cancer cells often acquire mutations that impair their ability to repair DNA damage effectively. This can lead to an accumulation of genetic mutations over time, which is a hallmark of cancer development. While some cancer cells may still have mechanisms to repair DNA damage, they are often less efficient compared to normal cells, leading to genomic instability and further mutation accumulation.
D.   Normal cells follow a tightly regulated cell cycle with specific checkpoints that ensure orderly progression through phases such as G1, S, G2, and M phases. In contrast, cancer cells often have dysregulated cell cycle control. They may bypass checkpoints that normally control cell division, leading to uncontrolled proliferation and growth.

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Correct Answer is B

Explanation

A. Headache is a common side effect of nitroglycerin due to its vasodilatory effects, especially in the head. Most headaches associated with nitroglycerin are mild and transient. Patients are generally advised to continue using the medication as prescribed unless the headache is severe or persistent.
B. Nitroglycerin tablets are used for the immediate relief of angina symptoms. If the first tablet does not adequately relieve chest pain within 5 minutes, the patient can take a second tablet. If the pain persists after the second tablet, emergency medical attention should be sought. However, it's important to note that the maximum number of tablets that can be taken within a short period should be specified by the healthcare provider, typically 2 or 3 tablets in 15 to 30 minutes.
C. Nitroglycerin can cause orthostatic hypotension, which is a drop in blood pressure upon standing up. This can lead to dizziness or fainting. Therefore, patients should be advised to stand up slowly after taking nitroglycerin to minimize the risk of falls or injury.
D. Nitroglycerin tablets are sensitive to light, heat, and moisture, which can reduce their effectiveness over time. Therefore, it's recommended to replace nitroglycerin tablets every 3 to 6 months to ensure potency and effectiveness.

A. Decreased dopamine B. Increased glial cells C. Increased glutamate D. Neurofibrillary tangles

Correct Answer is D

Explanation

A. Dopamine is primarily associated with other neurodegenerative disorders such as Parkinson's disease, not Alzheimer's disease. In Alzheimer's disease, the focus is on changes related to beta-amyloid plaques and neurofibrillary tangles rather than alterations in dopamine levels.
B. Glial cells, including astrocytes and microglia, play a role in the brain's immune response and support of neurons. In Alzheimer's disease, there is evidence of increased activation and proliferation of glial cells in response to neuroinflammation and the presence of beta-amyloid plaques and neurofibrillary tangles. This reactive gliosis is a secondary response to the underlying pathology.
C. Glutamate is an excitatory neurotransmitter involved in various brain functions, including memory and learning. In Alzheimer's disease, there is evidence of dysregulation in glutamate metabolism and

signaling pathways. This dysregulation can lead to excitotoxicity, which contributes to neuronal damage and cell death seen in the disease.
D. Neurofibrillary tangles are one of the hallmark pathological features of Alzheimer's disease. These tangles are aggregates of hyperphosphorylated tau protein that accumulate inside neurons, disrupting their normal functioning and eventually leading to cell death. Neurofibrillary tangles, along with beta- amyloid plaques, contribute to the progressive cognitive decline observed in Alzheimer's disease.

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Which of the following describes a characteristic of cancer cells?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client has been diagnosed with chronic stable angina and has a new prescription for nitroglycerin tablets. Which statement about this medication should the nurse include in the patient education?

Correct Answer is B

Explanation

Which pathophysiologic change is found in the brain tissue of people who have Alzheimer's disease?

Correct Answer is D

Explanation

A nurse is obtaining an admission history on a client who has possible asthma with new-onset wheezing and shortness of breath. Which information may be a cause of the client's bronchoconstriction?

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A nurse is caring for a client who has myasthenia gravis which has not responded to medication treatments. Which of the following surgeries can treat myasthenia gravis?

A nurse is caring for a client who has been diagnosed with heparin-induced thrombocytopenia (HIT). Which of the following clinical manifestations should the nurse recognize as the most concerning for a client with this condition?

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