Which laboratory test will the nurse use to determine whether filgrastim (Neupogen) is effective for a patient with acute lymphocytic leukemia who is receiving chemotherapy?
Reticulocyte count
White blood count / Absolute neutrophil count
Total lymphocyte count
Platelet count
The Correct Answer is B
A. Reticulocyte count: Reticulocyte count measures immature red blood cells and is not the primary measure for the effectiveness of filgrastim, which is used to boost white blood cells.
B. White blood count / Absolute neutrophil count: Filgrastim (Neupogen) is used to increase white blood cells, specifically neutrophils. Therefore, monitoring the white blood count (WBC) and absolute neutrophil count (ANC) is the appropriate way to determine the effectiveness of the drug.
C. Total lymphocyte count: While lymphocytes are a type of white blood cell, filgrastim primarily affects neutrophils, making WBC/ANC a better indicator.
D. Platelet count: Filgrastim does not directly impact platelet production, so platelet count is not the primary measure of its effectiveness.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["C","D"]
Explanation
A. The patient experiences a decrease in hemoglobin S. Hydroxyurea does not decrease hemoglobin S levels directly; it works by increasing fetal hemoglobin (Hgb F) levels.
B. The patient experiences dehydration due to diuresis. This is not an indication that Hydroxyurea is working; it is a potential side effect that should be monitored.
C. The patient experiences an increase in fetal hemoglobin (Hbg F). Hydroxyurea works by increasing the levels of fetal hemoglobin, which reduces the sickling of red blood cells.
D. The patient needs fewer blood transfusions. Successful treatment with Hydroxyurea should reduce the frequency of vaso-occlusive crises and the need for blood transfusions.
E. The patient experiences diuresis. This is not an indicator of the medication's effectiveness; it is a potential side effect.
Correct Answer is A
Explanation
A. The activity of the bone marrow is depressed. Aplastic anemia is a condition where the bone marrow fails to produce sufficient numbers of blood cells, including red cells, white cells, and platelets.
B. Red cells are absent as a result of chronic blood loss. This describes a condition like iron- deficiency anemia, not aplastic anemia.
C. The bone marrow fails to produce lymphocytes. Aplastic anemia affects the production of all blood cells, not just lymphocytes.
D. The kidneys fail to produce red blood cells. This describes anemia of chronic kidney disease, not aplastic anemia. In aplastic anemia, the problem lies with the bone marrow, not the kidneys.
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