Which laboratory test will the nurse use to determine whether filgrastim (Neupogen) is effective for a patient with acute lymphocytic leukemia who is receiving chemotherapy?
Reticulocyte count
White blood count / Absolute neutrophil count
Total lymphocyte count
Platelet count
The Correct Answer is B
A. Reticulocyte count: Reticulocyte count measures immature red blood cells and is not the primary measure for the effectiveness of filgrastim, which is used to boost white blood cells.
B. White blood count / Absolute neutrophil count: Filgrastim (Neupogen) is used to increase white blood cells, specifically neutrophils. Therefore, monitoring the white blood count (WBC) and absolute neutrophil count (ANC) is the appropriate way to determine the effectiveness of the drug.
C. Total lymphocyte count: While lymphocytes are a type of white blood cell, filgrastim primarily affects neutrophils, making WBC/ANC a better indicator.
D. Platelet count: Filgrastim does not directly impact platelet production, so platelet count is not the primary measure of its effectiveness.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Radiation exposure: Radiation exposure can cause aplastic anemia, but if the cause is unknown, it is less likely to be due to a specific and identifiable event like radiation exposure.
B. An autoimmune disorder: When the cause of aplastic anemia cannot be diagnosed, it is often attributed to an autoimmune disorder where the body attacks its own bone marrow cells.
C. Chemotherapy drugs: Chemotherapy drugs can cause aplastic anemia, but this cause would typically be known based on the patient's medical history.
D. Toxins: Toxins can cause aplastic anemia, but like chemotherapy drugs and radiation, this cause would generally be identifiable.
Correct Answer is C
Explanation
A. Clotting is not directly related to the destruction of red blood cells.
B. Cyanosis refers to a bluish discoloration of the skin due to poor circulation or inadequate oxygenation, which is not directly indicative of red blood cell destruction.
C. Jaundice is the yellowing of the skin and eyes caused by the buildup of bilirubin, a byproduct of the destruction of red blood cells, which is a common symptom of hemolytic anemia.
D. Bleeding is not a symptom associated with the destruction of red blood cells but rather a lack of clotting factors or platelets.
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