Which is(are) potential result(s) of end-organ damage from chronic hypertension? (Select all that apply.)
Cardiac disease
Renal insufficiency
Stroke
Familial hypercholesterolemia
Atrial fibrillation
Isolated systolic hypertension
Correct Answer : A,B,C,E
A. Chronic hypertension is a significant risk factor for the development of various cardiac diseases, including coronary artery disease, left ventricular hypertrophy, heart failure, and arrhythmias. The increased workload on the heart caused by hypertension can lead to myocardial remodeling, impaired cardiac function, and ultimately heart disease.
B. Chronic hypertension can cause damage to the kidneys over time, leading to renal insufficiency or chronic kidney disease. The elevated blood pressure damages the delicate blood vessels in the kidneys, impairing their ability to filter waste products and regulate fluid and electrolyte balance. Persistent hypertension can ultimately lead to kidney dysfunction and renal failure.
C. Hypertension is a major risk factor for the development of stroke, particularly ischemic stroke (caused by a blockage in a blood vessel supplying the brain) and hemorrhagic stroke (caused by bleeding into the brain). Chronic hypertension can damage blood vessels in the brain, leading to the formation of blood clots or weakening of vessel walls, increasing the risk of stroke.
E. Chronic hypertension is a significant risk factor for the development of atrial fibrillation, a type of irregular heart rhythm characterized by rapid and chaotic electrical activity in the upper chambers of the heart (atria). The structural changes in the heart caused by hypertension, such as left atrial enlargement and fibrosis, can predispose individuals to atrial fibrillation.
D. Familial hypercholesterolemia is a genetic disorder characterized by high levels of LDL cholesterol in the blood. While chronic hypertension itself does not directly cause familial hypercholesterolemia, hypertension and hypercholesterolemia are often comorbid conditions that contribute to cardiovascular risk. Both conditions can lead to atherosclerosis, increasing the risk of heart disease and stroke.
F. Isolated systolic hypertension refers to elevated systolic blood pressure with normal diastolic blood pressure. While isolated systolic hypertension itself is a manifestation of hypertension, it is not a direct result of end-organ damage. However, if left untreated, isolated systolic hypertension can lead to complications such as stroke, heart failure, and kidney disease, which are consequences of end-organ damage from chronic hypertension.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","C","D","E"]
Explanation
A. Hypotension may result from decreased cardiac output due to hypoxemia and acidosis or as a compensatory response to hypoxia-induced vasodilation. Therefore, monitoring for hypotension is important in ARF.
C. Hypoxemia can impair cerebral perfusion and neuronal function, leading to alterations in mental status ranging from confusion to coma. Decreased level of consciousness is a concerning sign of inadequate oxygenation and should be closely monitored in patients with ARF.
D. Dyspnea, or difficulty breathing, is a hallmark symptom of respiratory failure. In ARF, the respiratory system's inability to adequately oxygenate or ventilate leads to increased work of breathing and feelings of breathlessness. Patients with ARF often experience severe dyspnea as they struggle to maintain adequate gas exchange.
E. Headache is not typically considered a primary manifestation of ARF. However, it may occur as a secondary symptom due to factors such as hypoxemia, hypercapnia, or acidosis. Patients with ARF may experience headache as a result of cerebral vasodilation in response to hypoxia or as a symptom of underlying conditions contributing to respiratory failure.
B. Nausea is not a typical manifestation of ARF itself. However, it may occur as a secondary symptom due to factors such as hypoxia, acidosis, or medications administered for the management of ARF. While nausea may be present, it is not a direct result of respiratory failure.
Correct Answer is A
Explanation
A. Atropine is commonly used in the treatment of symptomatic bradycardia. It works by blocking vagal stimulation, leading to increased heart rate. Atropine is typically administered in doses of 0.5 to 1 mg every 3 to 5 minutes, up to a total dose of 3 mg, in patients with symptomatic bradycardia.
B. Sodium bicarbonate is not indicated for symptomatic bradycardia. It is primarily used in the management of metabolic acidosis, hyperkalemia, and certain drug overdoses. While sodium bicarbonate may be administered in specific situations during cardiopulmonary resuscitation (CPR), it is not the first-line treatment for symptomatic bradycardia.
C. Magnesium sulfate is used in the treatment of certain arrhythmias, such as torsades de pointes and refractory ventricular fibrillation or ventricular tachycardia associated with hypomagnesemia. However, it is not the first-line treatment for symptomatic bradycardia. Magnesium sulfate may be considered if there are specific indications such as torsades de pointes or suspected hypomagnesemia.
D. Epinephrine is commonly used in advanced cardiac life support (ACLS) protocols for cardiac arrest. It is not the first-line treatment for symptomatic bradycardia. Epinephrine is primarily used during CPR to improve coronary and cerebral perfusion by increasing systemic vascular resistance and heart rate.
However, in the case of symptomatic bradycardia, atropine is typically preferred as the initial medication.
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