Which is the treatment of choice for severe aplastic anemia?

Bone marrow transplantation

Exchange transfusion

Liver transplantation

Administration of intravenous immunoglobulin

Answer and Explanation

The Correct Answer is A

A. Bone marrow transplantation.

Severe aplastic anemia is a condition characterized by a significant reduction in the number of blood cells produced by the bone marrow. The primary treatment for severe aplastic anemia is a bone marrow transplantation, also known as a stem cell transplant. This procedure involves replacing the patient's dysfunctional bone marrow with healthy bone marrow or stem cells from a suitable donor. This is done to restore normal blood cell production.

Option B (Exchange transfusion) is not the primary treatment for severe aplastic anemia but may be used in certain cases to manage complications or specific symptoms.

Option C (Liver transplantation) is not a treatment for severe aplastic anemia, as this condition primarily affects the bone marrow and blood cell production.

Option D (Administration of intravenous immunoglobulin) is not the primary treatment for severe aplastic anemia but may be used in some cases to manage complications, such as infections. However, it does not address the underlying cause of the disease, which is the failure of the bone marrow to produce enough blood cells.

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Correct Answer is D

Explanation

Option A, "Fatigue," is a symptom of anemia but is not a long-term complication associated with Thalassemia major.

Option B, "Deferoxamine usage," is a treatment to manage iron overload and not a complication associated with Thalassemia major.

Option C, "Immunosuppressive therapy," is not typically used to manage Thalassemia major and is not a long-term complication but rather a potential treatment for certain cases of thalassemia.

Option D. Hemochromatosis/Hemosiderosis

Thalassemia major is a genetic disorder that results in the body's inability to produce enough hemoglobin, leading to severe anemia.

To manage this condition, frequent blood transfusions are required, which can lead to iron overload in the body. Excess iron gets deposited in various organs and tissues, causing damage.

Hemochromatosis or hemosiderosis is a condition characterized by the accumulation of iron in organs like the liver, heart, and endocrine glands, which can result from repeated blood transfusions.

The complications associated with iron overload include liver damage, heart problems, diabetes, and more. Treatment with iron chelating agents like deferoxamine is often necessary to remove excess iron from the body.

A. Lordosis B. Torticollis C. Scoliosis D. Kyphosis

Correct Answer is C

Explanation

A. Lordosis: Lordosis is an excessive inward curvature of the spine, typically seen in the lower back. It is often referred to as "swayback."

B. Torticollis: Torticollis is a condition where the head is tilted to one side and may be rotated to the opposite side. It typically affects the neck muscles and is not related to lateral curvature of the spine.

C. Scoliosis.

Scoliosis is a lateral curvature of the spine. It is characterized by an abnormal sideways curvature of the spine, which can lead to an "S" or "C" shape of the spine. Scoliosis can occur during adolescence, and routine physical examinations may reveal this condition.

D. Kyphosis: Kyphosis is an excessive outward curvature of the spine, which can result in a rounded or hunched back, often seen in the upper back or thoracic spine.

In summary, the lateral curvature of the spine observed in this adolescent should be documented as scoliosis.

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Which is the treatment of choice for severe aplastic anemia?

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Naxlex Comprehensive Predictor Exams

A long-term complication sees in Thalassemia major are associated to which of the following?

Correct Answer is D

Explanation

A nurse is assisting with a routine physical examination of an adolescent. The provider observes a lateral curvature of the spine. The nurse should expect the provider to document which of the following disorders?

Correct Answer is C

Explanation

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