The physician orders a Lidocaine drip to infuse at 2 mg/min. The drug is available as 2 gm in 500 ml of fluid. Solve for ml/hr.

A. The use-even one time-of any substance: Too broad and does not specify harm or misuse. Using a prescribed medication once wouldn't necessarily be misuse.

B. The use of a psychoactive compound/drug/substance in an amount or frequency that causes harm to the person or others. Defines misuse as harmful use impacting health or safety. Substance misuse involves using substances in a way that causes harm, which can include physical, psychological, or social consequences.

C. The use of any substance in a manner, situation, amount or frequency that can cause harm to users or to those around them: While this choice highlights potential harm, it lacks specificity regarding psychoactive substances. It’s a broader concept that may include non-psychoactive substances as well.

D. The use of a psychoactive compound/drug/substance that poses hazards to health and impacts all aspects of the client's life: This definition is comprehensive but not as succinct as choice B. It encompasses physical, psychological, and social consequences of substance misuse.

A. "It's uncontrolled proliferative cell growth that is cancerous." Describes cancerous growth, not hypertrophy.

B. "It's the enlargement of an organ or tissue from the increase in cell size." Defines cellular hypertrophy accurately. Hypertrophy involves an increase in the size of cells, leading to the enlargement of tissues or organs, often in response to increased workload or stimulation.

C. "It's the wasting away of tissue or organs." Describes atrophy, not hypertrophy.

D. "It's the abnormal growth or development of cells." Broad definition that does not specifically describe hypertrophy.