The nurse receives a prescription for ciprofloxacin 400 mg intravenously (IV) every 12 hours to be infused over an hour. The IV bag contains ciprofloxacin 400 mg in dextrose 5% in water (D5W) 200 mL. The nurse should program the infusion pump to deliver how many mL/hr? (Enter numerical value only.)

Choice A reason: Breast feeding is not recommended while taking this medication, as isotretinoin can pass into breast milk and harm

the nursing infant. However, this information is not as important as choice d, as the client may not be breast feeding or planning to breast feed.

Choice B reason: Baseline liver function results must be obtained during therapy, as isotretinoin can cause liver damage and increase liver enzymes. However, this information is not as important as choice d, as the client may not have liver problems or need liver function tests.

Choice C reason: Do not take multiple vitamins that contain vitamin A while taking this drug, as isotretinoin is a derivative of vitamin A and can cause vitamin A toxicity if taken in excess. However, this information is not as important as choice d, as the client may not take multiple vitamins or have vitamin A toxicity.

Choice D reason: Discontinue this medication one month before attempting to conceive, as isotretinoin can cause severe birth defects and miscarriages if taken during pregnancy. Therefore, this information is most important for the nurse to provide this client, as the client is planning to become pregnant and should avoid isotretinoin exposure.

Choice A reason: Administering levothyroxine at bedtime is not a correct statement, as it may interfere with sleep quality and hormone absorption. Levothyroxine is a synthetic thyroid hormone that replaces or supplements low levels of natural thyroid hormone in hypothyroidism. Levothyroxine should be taken in the morning, at least 30 minutes before breakfast, to avoid insomnia and ensure optimal absorption.

Choice B reason: Consuming foods that are high in iodine is not a correct statement, as it may affect thyroid function and hormone levels. Iodine is an essential element that is needed for thyroid hormone synthesis. However, too much or too little iodine can cause thyroid disorders, such as goiter or hyperthyroidism. Levothyroxine does not require additional iodine intake, and clients should follow a balanced diet.

Choice C reason: Avoiding the use of iron supplements is a correct statement, but it is not specific to levothyroxine. Iron supplements can interfere with many medications, including levothyroxine, by reducing their absorption and efficacy. Iron supplements should be taken at least 4 hours before or after levothyroxine or other medications.

Choice D reason: Taking medication on an empty stomach is a correct statement that indicates effective education. Levothyroxine should be taken on an empty stomach, preferably in the morning, to avoid food-drug interactions and enhance absorption. Food, especially those high in fiber or calcium, can decrease levothyroxine absorption and effectiveness.