The nurse is caring for a client who is taking simvastatin (Zocor). What should the nurse instruct this client to avoid while taking this medication?
Orange juice
Coenzyme Q10 (CoQ10) supplements
Grapefruit juice
All fruit juices
The Correct Answer is C
A. Orange juice does not interact with simvastatin and does not need to be avoided.
B. Coenzyme Q10 (CoQ10) supplements are sometimes taken by patients on statins to help alleviate the side effects like muscle pain, but they do not need to be avoided.
C. Grapefruit juice should be avoided while taking simvastatin because it contains compounds that interfere with the enzymes that metabolize statins, potentially leading to increased drug levels and greater risk of side effects such as muscle damage.
D. Not all fruit juices interact with simvastatin; the specific concern is with grapefruit juice.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Organic nitrates do not increase contractility and heart rate; they typically decrease myocardial oxygen demand.
B. Organic nitrates do not slow heart rate or decrease contractility of the heart.
C. The mechanism of action of organic nitrates in the treatment of angina is the relaxation of arterial and venous smooth muscle, leading to vasodilation and decreased myocardial oxygen demand.

D. Organic nitrates do not increase peripheral resistance; they typically cause vasodilation.
Correct Answer is ["B","C","E"]
Explanation
A. ACE inhibitors may be started later to manage heart failure or hypertension after a heart attack but are not typically given acutely during a myocardial infarction.
B. Thrombolytics, such as alteplase, are given as soon as possible after a heart attack to dissolve the blood clot causing the blockage in the coronary artery.
C. Aspirin is commonly administered during a heart attack to help prevent further clot formation and reduce the risk of complications.
D. Potassium-sparing diuretics are not typically given during a myocardial infarction but may be used later in the management of heart failure.
E. Beta blockers are commonly given during and after a heart attack to reduce the heart's workload, decrease oxygen demand, and improve survival rates.
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