Marie Garcia, age 67, reports that her chronic angina has been recurring even though she has been taking nitroglycerin sublingual tablets as prescribed. She tells the nurse that she used to store the tablets on a table by the window, and when she started to use a new batch of tablets, the problem subsided. What I would explain the ineffectiveness of the tablets?
Ms. Garcia developed unstable angina
Exposure to the elements (natural light) caused the drugs to lose their effectiveness
Ms. Garcia developed tolerance to the sublingual form of administration
Ms. Garcia did not follow the correct interval or duration of administration
The Correct Answer is B
Explanation:
A. There is no evidence in the scenario to suggest that Ms. Garcia developed unstable angina.
B. Exposure to light, particularly sunlight, can degrade nitroglycerin, reducing its effectiveness over time.
C. There is no indication that Ms. Garcia developed tolerance to sublingual nitroglycerin in this scenario.
D. Ms. Garcia's storage method for the nitroglycerin tablets, not the interval or duration of administration, likely affected their effectiveness.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Suspended release formulations typically have a slower onset of action compared to sublingual administration.
B. Transdermal patches provide a slow, continuous release of nitroglycerin and do not offer rapid onset.
C. Topical ointments have a slower onset of action compared to sublingual administration.
D. Sublingual administration of nitroglycerin provides the most rapid onset of action due to direct absorption through the oral mucosa.
Correct Answer is D
Explanation
A. Taking cholestyramine with food may interfere with its absorption, reducing its effectiveness.
B. Taking cholestyramine without food is not typically recommended.
C. Taking cholestyramine in the morning is not specifically indicated; it can be taken at any time of the day.
D. Taking cholestyramine with large amounts of fluid helps prevent gastrointestinal side effects and improves its effectiveness in lowering cholesterol levels.
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