Marie Garcia, age 67, reports that her chronic angina has been recurring even though she has been taking nitroglycerin sublingual tablets as prescribed. She tells the nurse that she used to store the tablets on a table by the window, and when she started to use a new batch of tablets, the problem subsided. What I would explain the ineffectiveness of the tablets?
Ms. Garcia developed unstable angina
Exposure to the elements (natural light) caused the drugs to lose their effectiveness
Ms. Garcia developed tolerance to the sublingual form of administration
Ms. Garcia did not follow the correct interval or duration of administration
The Correct Answer is B
Explanation:
A. There is no evidence in the scenario to suggest that Ms. Garcia developed unstable angina.
B. Exposure to light, particularly sunlight, can degrade nitroglycerin, reducing its effectiveness over time.
C. There is no indication that Ms. Garcia developed tolerance to sublingual nitroglycerin in this scenario.
D. Ms. Garcia's storage method for the nitroglycerin tablets, not the interval or duration of administration, likely affected their effectiveness.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A. Aspirin is not primarily used to inhibit peptic ulcer disease; it is used to prevent cardiovascular events by decreasing platelet aggregation.
B. Aspirin decreases platelet aggregation, making it useful in preventing clot formation in conditions such as angina and myocardial infarction.
C. Aspirin is not used to reduce emphysema; it is primarily used for its antiplatelet effects.
D. Aspirin does not directly decrease carbon dioxide retention; its primary mechanism of action in cardiovascular disease is through antiplatelet effects.
Correct Answer is C
Explanation
A. Organic nitrates do not increase contractility and heart rate; they typically decrease myocardial oxygen demand.
B. Organic nitrates do not slow heart rate or decrease contractility of the heart.
C. The mechanism of action of organic nitrates in the treatment of angina is the relaxation of arterial and venous smooth muscle, leading to vasodilation and decreased myocardial oxygen demand.

D. Organic nitrates do not increase peripheral resistance; they typically cause vasodilation.
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