The nurse is caring for a client who is taking diclofenac, a nonsteroidal anti-inflammatory (NSAID) drug for rheumatoid arthritis. During a clinic visit, the client appears pale and reports increasing fatigue. Which of the client's serum laboratory values is most important for the nurse to review?

Glucose.

Total protein.

Sodium.

Hemoglobin.

Answer and Explanation

The Correct Answer is D

Choice A reason: This is not the most important laboratory value for the nurse to review. Glucose is a measure of blood sugar levels, and it may be affected by various factors, such as diet, medication, stress, or infection. However, glucose is not directly related to the use of diclofenac or the symptoms of the client. The nurse should monitor the glucose levels for any changes, but it is not the priority.

Choice B reason: This is not the most important laboratory value for the nurse to review. Total protein is a measure of the amount of protein in the blood, and it may reflect the nutritional status, liver function, or kidney function of the client. However, total protein is not directly related to the use of diclofenac or the symptoms of the client. The nurse should monitor the total protein levels for any changes, but it is not the priority.

Choice C reason: This is not the most important laboratory value for the nurse to review. Sodium is a measure of the electrolyte balance in the blood, and it may be affected by fluid intake, fluid loss, or hormonal regulation. However, sodium is not directly related to the use of diclofenac or the symptoms of the client. The nurse should monitor the sodium levels for any changes, but it is not the priority.

Choice D reason: This is the most important laboratory value for the nurse to review. Hemoglobin is a measure of the oxygen-carrying capacity of the blood, and it may indicate the presence of anemia, which is a common adverse effect of diclofenac. Diclofenac can cause gastrointestinal bleeding, which can lead to a decrease in hemoglobin and hematocrit levels. The client's appearance and fatigue may be signs of anemia, which can impair the tissue oxygenation and worsen the client's condition. The nurse should review the hemoglobin levels and report any abnormal findings to the healthcare provider. The nurse should also assess the client for other signs of bleeding, such as melena, hematemesis, or hematuria.

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Correct Answer is A

Explanation

Choice A reason: This is the most significant information about this finding. St. John's Wort is an herbal supplement that is used for various conditions, such as depression, anxiety, or insomnia. However, it can also interact with many medications, including cyclosporine, which is an immunosuppressant drug that is used to prevent organ rejection after transplantation. St. John's Wort can induce the activity of certain enzymes in the liver that metabolize cyclosporine, leading to lower levels of the drug in the blood and reduced efficacy. This can increase the risk of graft rejection and complications. The nurse should inform the healthcare provider and educate the client about the potential interaction and the importance of avoiding St. John's Wort and other herbal products without consulting the provider.

Choice B reason: This is not significant information about this finding. Adding the herb can not decrease the need for corticosteroids, which are another type of immunosuppressant drug that are used to prevent organ rejection after transplantation. St. John's Wort does not have any anti-inflammatory or immunomodulatory effects that can reduce the dosage or frequency of corticosteroids. On the contrary, it can interfere with the metabolism and absorption of corticosteroids, as well as other medications, and cause adverse effects or reduced efficacy. The nurse should advise the client to follow the prescribed regimen of corticosteroids and other drugs, and not to self-medicate with herbal products.

Choice C reason: This is not significant information about this finding. The client probably used this herb to treat depression, which is a common condition among transplant recipients, due to the stress, anxiety, and lifestyle changes associated with the procedure. However, this does not explain the cause of the graft rejection, nor does it justify the use of St. John's Wort without consulting the healthcare provider. St. John's Wort is not a proven or safe treatment for depression, and it can interact with many antidepressant drugs, such as selective serotonin reuptake inhibitors (SSRIs), and cause serious side effects, such as serotonin syndrome. The nurse should assess the client's mental health status and refer the client to a mental health professional if needed.

Choice D reason: This is not a significant information about this finding. Ingestion of St. John's Wort can not reduce the client's intake of sodium, which is an electrolyte that is essential for the fluid balance and nerve function in the body. St. John's Wort does not have any diuretic or sodium-lowering effects that can affect the sodium levels in the blood or urine. The nurse should monitor the client's sodium levels and fluid intake and output, and report any abnormal findings to the healthcare provider. The nurse should also teach the client about the dietary sources and recommendations of sodium, and the signs and symptoms of hyponatremia or hypernatremia.

A. Serum ammonia level of 30 Mcg/dL (17.62 mmol/L). B. Hemoglobin level of 13.5 g/dL (135 g/L). C. Serum potassium level of 3.8 mEq/L (3.8 mmol/L). D. Serum glucose level of 120 mg/dL (6.7 mmol/L).

Correct Answer is C

Explanation

Choice A reason: This is not the laboratory finding that indicates that the medication has been effective. Serum ammonia level of 30 Mcg/dL (17.62 mmol/L) is within the normal range for adults, and it does not reflect the effect of sodium polystyrene sulfonate. Sodium polystyrene sulfonate is a cation-exchange resin that binds to potassium in the intestine and removes it from the body through the stool. It does not affect the ammonia levels in the blood, which are influenced by the liver function and the urea cycle. The nurse should monitor the ammonia levels for any changes, but it is not the goal of the medication.

Choice B reason: This is not the laboratory finding that indicates that the medication has been effective. Hemoglobin level of 13.5 g/dL (135 g/L) is within the normal range for females, and it does not reflect the effect of sodium polystyrene sulfonate. Sodium polystyrene sulfonate does not affect the hemoglobin levels in the blood, which are determined by the number and size of red blood cells and the oxygen-carrying capacity of the blood. The nurse should monitor the hemoglobin levels for any changes, but it is not the goal of the medication.

Choice C reason: This is the laboratory finding that indicates that the medication has been effective. Serum potassium level of 3.8 mEq/L (3.8 mmol/L) is within the normal range for adults, and it indicates that the medication has lowered the potassium levels in the blood. Sodium polystyrene sulfonate is used to treat hyperkalemia, or high potassium levels, which can occur in AKI due to the impaired renal excretion of potassium. Hyperkalemia can cause cardiac arrhythmias, muscle weakness, and paralysis. The nurse should administer sodium polystyrene sulfonate as prescribed and check the serum potassium levels regularly to ensure that they are within the normal range.

Choice D reason: This is not the laboratory finding that indicates that the medication has been effective. Serum glucose level of 120 mg/dL (6.7 mmol/L) is slightly above the normal range for adults, and it does not reflect the effect of sodium polystyrene sulfonate. Sodium polystyrene sulfonate does not affect the glucose levels in the blood, which are influenced by the carbohydrate metabolism and the insulin secretion and action. The nurse should monitor the glucose levels for any changes, but it is not the goal of the medication.

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The nurse is caring for a client who is taking diclofenac, a nonsteroidal anti-inflammatory (NSAID) drug for rheumatoid arthritis. During a clinic visit, the client appears pale and reports increasing fatigue. Which of the client's serum laboratory values is most important for the nurse to review?

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Correct Answer is A

Explanation

The nurse is administering sodium polystyrene sulfonate to a client in acute kidney injury (AKI). Which laboratory finding indicates that the medication has been effective?

Correct Answer is C

Explanation

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