A client is receiving intravenous (IV) vancomycin and the nurse plans to draw blood for a peak and trough to determine the serum level of the drug. Which collection times provide the best determination of these levels?
Two hours after completion of the IV dose and two hours before the next administration of the medication.
One hour after completion of the IV dose and one hour before the next administration of the medication.
Thirty minutes into the administration of the IV dose and 30 minutes before the next administration of the medication.
Immediately after completion of the IV dose and 30 minutes before the next administration of the medication.
None
None
The Correct Answer is B
choice A, Drawing the peak level two hours after the IV dose is too late to capture the drug's highest serum concentration. Similarly, drawing the trough two hours before the next dose does not reflect the lowest drug level accurately.
Choice B, Drawing the peak level one hour after completion of the IV dose ensures an accurate measurement of the highest serum concentration, as vancomycin typically peaks within this time frame. Drawing the trough one hour before the next dose ensures the lowest concentration of the drug is measured, providing precise therapeutic monitoring.
Choice C is incorrect because drawing blood 30 minutes into the IV dose would not allow the full dose to circulate and reach peak levels in the bloodstream.
Choice D. Drawing the peak level immediately after the completion of the IV dose is too early, as the drug needs time to distribute in the bloodstream and reach its highest concentration. While drawing the trough 30 minutes before the next dose is appropriate, the incorrect timing of the peak makes this option unsuitable.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
The correct answer is D.
Choice A rationale: While iodine is essential for thyroid hormone synthesis, it is not relevant to the administration of levothyroxine. The client does not need to consume foods high in iodine specifically for taking levothyroxine.
Choice B rationale: While iron supplements can interfere with the absorption of levothyroxine, this statement does not indicate that the client understands when to take levothyroxine correctly.
Choice C rationale: Levothyroxine should be taken in the morning, not at bedtime, to avoid interference with sleep and to optimize absorption.
Choice D rationale: Levothyroxine, a thyroid hormone replacement, should be taken on an empty stomach, preferably in the morning, at least 30 minutes before eating. Taking it on an empty stomach maximizes its absorption and ensures optimal therapeutic effects.
Correct Answer is B
Explanation
Relief of depression Incorrect because anticholinergics do not have antidepressant effects and may worsen depression by causing sedation, confusion or hallucinations.
Decreased tremors Correct because anticholinergics block the action of acetylcholine in the brain and reduce the imbalance between dopamine and acetylcholine that causes tremors in Parkinson's disease.
Delay in disease progression Incorrect because anticholinergics do not modify the underlying pathology of Parkinson's disease and do not prevent neuronal degeneration or dopamine depletion.
Improved bladder function Incorrect because anticholinergics may impair bladder function by causing urinary retention, hesitancy or incontinence due to their antispasmodic effects on the detrusor muscle.
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