The nurse is caring for a client who is 21-weeks pregnant and requires the administration of various medications. The nurse understands that different medications are classified on their potential interaction with the mother's fetus. From the list of options below, match the correct medication category to its corresponding description.

Category A- indicate no risk to the human fetus.

Category C- medications indicated possible risk in humans has been reported.

Category X - medications have reportable fetal abnormalities associated with consumption. Positive evidence of fetal risk is available in both humans and animals

Category B -Studies indicate no risk to the animal fetus, with no information on human fetuses available.

Answer and Explanation

Correct Answer : A,B,C,D

A. Category A:
Medications classified as Category A are considered the safest during pregnancy. They have been well-studied in pregnant humans, and no risk to the fetus has been demonstrated. This classification means that adequate and well-controlled studies have shown no evidence of harm to the fetus in the first trimester and no risk in later trimesters.

B. Category C:
Category C medications have shown potential risks to the fetus in animal studies, and there are no well-controlled studies in humans. The benefits of the medication may outweigh the potential risks, but caution is advised. These medications are used when the potential benefits justify the potential risks to the fetus.

C. Category X:
Category X medications are contraindicated in pregnancy due to evidence of fetal abnormalities or risks that outweigh any potential benefits. These medications have demonstrated clear evidence of harm to the fetus in both human and animal studies, and their use is not recommended during pregnancy.

D. Category B:
Category B medications have shown no risk to animal fetuses, but there is a lack of adequate and well-controlled studies in pregnant humans. The absence of evidence of harm in animal studies suggests that these drugs are generally considered safe, though their effects on human fetuses are not well-documented.

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Correct Answer is ["B","C","E"]

Explanation

A) Parenteral medications are avoided due to fragility of veins: While it is true that older adults may have fragile veins, this does not mean that parenteral medications are universally avoided. Parenteral medications are still used based on clinical needs, though careful consideration is given to the condition of the veins.

B) Older adults are at risk for drug toxicity due to accumulation in the body: This is correct. As people age, their liver and kidney functions often decline, leading to decreased metabolism and excretion of drugs. This can result in drug accumulation and an increased risk of toxicity.

C) The elderly population is susceptible to polypharmacy: This is correct. Older adults often take multiple medications for various chronic conditions, increasing the risk of drug interactions, side effects, and complications. Polypharmacy is a common issue in this population.

D) Medication metabolism tends to be faster in older adults: This is incorrect. Medication metabolism generally slows down in older adults due to decreased liver function. Slower metabolism can lead to drug accumulation and increased risk of adverse effects.

E) Older adults have delayed absorption: This is correct. Although the rate of absorption may not be significantly affected, the overall absorption can be altered due to changes in gastrointestinal function and blood flow in older adults.

A. Does not have an effect B. Increases C. Decreases D. Enhances

Correct Answer is C

Explanation

A) Does not have an effect: Food can significantly affect drug dissolution and absorption, so it is not accurate to say it has no effect. The presence of food in the gastrointestinal tract can alter how drugs are absorbed.

B) Increases: While food can sometimes increase the absorption of certain medications by stimulating digestive processes, it generally does not increase drug absorption for all medications. In many cases, food can delay or decrease the rate of drug absorption.

C) Decreases: Food commonly decreases the rate and extent of drug absorption. This can occur because food may bind to the drug, alter the pH of the stomach, or affect gastric emptying, leading to reduced drug dissolution and absorption.

D) Enhances: Food generally does not enhance drug dissolution and absorption for most medications. While some medications are better absorbed with food, in many cases, food can reduce the rate at which a drug is absorbed, leading to decreased efficacy.

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Naxlex Comprehensive Predictor Exams

A nurse is caring for an older adult client. The nurse should recognize that which of the following considerations apply to older adults and pharmacology? (Select all that apply).

Correct Answer is ["B","C","E"]

Explanation

A client asks why she needs to take a medication on an empty stomach. The nurse explains that food generally has which effect on drug dissolution and absorption?

Correct Answer is C

Explanation

A nurse is preparing an in-service program about preventing medication errors when transcribing a prescription. The nurse is using a dosage example of two tenths of a milligram. Which of the following examples should the nurse use to show appropriate transcription of this dosage?

The healthcare provider orders Ceftriaxone 20 mg IV every 6 hours. The instructions say to reconstitute 10 mg of Ceftriaxone with 6.5 ml of normal saline for a final concentration of 5 mg/ml. How many mL would the nurse administer? (Round to the nearest tenth)

A nurse is teaching with a group of nurses about the administration of nitroglycerin. Which of the following routes of administration provides the most rapid onset for the client?

A nurse is reviewing a client's prescribed medications. Which of the following situations represents a contraindication to medication administration?

Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.

A nurse is preparing to administer a medication to a client who states, "That looks different from the pill I usually take." Which is the best response by the nurse?

A client presents to the healthcare setting with a diagnosis of chronic liver failure. The nurse understands this will affect which step of pharmacokinetics?