Select the correct order in which pharmacokinetics process occur when a medication is taken via the oral route.
Distribution, Excretion, Absorption Metabolism
Absorption, Excretion, Metabolism, Distribution
Absorption, Distribution, Metabolism. Excretion
Absorption, Metabolism, Distribution, Excretion
The Correct Answer is C
A) Distribution, Excretion, Absorption, Metabolism: This order is incorrect because absorption should occur before distribution. The medication must first be absorbed into the bloodstream before it can be distributed throughout the body. Excretion and metabolism follow after distribution, not before.
B) Absorption, Excretion, Metabolism, Distribution: This sequence is incorrect because distribution occurs after absorption and before metabolism. Excretion is the final step and occurs after metabolism.
C) Absorption, Distribution, Metabolism, Excretion: This is the correct order. After oral administration, the medication is first absorbed into the bloodstream from the gastrointestinal tract. It is then distributed throughout the body. Following distribution, the medication undergoes metabolism (primarily in the liver) to be converted into more water-soluble forms for elimination. Finally, the medication is excreted from the body, typically through the kidneys
D) Absorption, Metabolism, Distribution, Excretion: This order is incorrect because metabolism occurs after distribution, not before. After absorption, the drug must be distributed to various tissues before it is metabolized. Excretion is the final step following metabolism.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is {"A":{"answers":"C"},"B":{"answers":"D"},"C":{"answers":"A"},"D":{"answers":"B"}}
Explanation
Naloxone is an opioid antagonist and is used to reverse opioid overdoses.
Flumazenil is a benzodiazepine antagonist and can reverse the effects of benzodiazepines.
Glucagon can be used to treat beta-blocker overdose by increasing heart rate and blood pressure.
Acetylcysteine acts as an antidote for acetaminophen toxicity by replenishing glutathione levels to enhance non-toxic metabolism of acetaminophen.
Correct Answer is C
Explanation
A) Distribution, Excretion, Absorption, Metabolism: This order is incorrect because absorption should occur before distribution. The medication must first be absorbed into the bloodstream before it can be distributed throughout the body. Excretion and metabolism follow after distribution, not before.
B) Absorption, Excretion, Metabolism, Distribution: This sequence is incorrect because distribution occurs after absorption and before metabolism. Excretion is the final step and occurs after metabolism.
C) Absorption, Distribution, Metabolism, Excretion: This is the correct order. After oral administration, the medication is first absorbed into the bloodstream from the gastrointestinal tract. It is then distributed throughout the body. Following distribution, the medication undergoes metabolism (primarily in the liver) to be converted into more water-soluble forms for elimination. Finally, the medication is excreted from the body, typically through the kidneys
D) Absorption, Metabolism, Distribution, Excretion: This order is incorrect because metabolism occurs after distribution, not before. After absorption, the drug must be distributed to various tissues before it is metabolized. Excretion is the final step following metabolism.
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