A client asks why she needs to take a medication on an empty stomach. The nurse explains that food generally has which effect on drug dissolution and absorption?
Does not have an effect
Increases
Decreases
Enhances
The Correct Answer is C
A) Does not have an effect: Food can significantly affect drug dissolution and absorption, so it is not accurate to say it has no effect. The presence of food in the gastrointestinal tract can alter how drugs are absorbed.
B) Increases: While food can sometimes increase the absorption of certain medications by stimulating digestive processes, it generally does not increase drug absorption for all medications. In many cases, food can delay or decrease the rate of drug absorption.
C) Decreases: Food commonly decreases the rate and extent of drug absorption. This can occur because food may bind to the drug, alter the pH of the stomach, or affect gastric emptying, leading to reduced drug dissolution and absorption.
D) Enhances: Food generally does not enhance drug dissolution and absorption for most medications. While some medications are better absorbed with food, in many cases, food can reduce the rate at which a drug is absorbed, leading to decreased efficacy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A) Naloxone: Naloxone is an opioid antagonist used to reverse the effects of opioid overdose, including respiratory depression. Given that the client has overdosed on morphine and is exhibiting a critically low respiratory rate of 6/min, naloxone is the appropriate medication to administer to reverse the effects of morphine and restore normal breathing.
B) Flumazenil: Flumazenil is a benzodiazepine antagonist used to reverse the effects of benzodiazepine overdose. It is not effective for opioid overdoses, such as those caused by morphine.
C) Protamine: Protamine is used to reverse the effects of heparin, an anticoagulant, and is not relevant in the context of opioid overdose. It does not address the respiratory depression caused by morphine.
D) Epinephrine: Epinephrine is used in cases of anaphylaxis or severe allergic reactions and is not appropriate for reversing opioid overdose. It would not address the respiratory depression caused by morphine overdose.
Correct Answer is ["A","F"]
Explanation
A. St. John's wort 450 mg by mouth twice daily: St. John's wort is known to be a potent inducer of cytochrome P450 enzymes and can significantly reduce the effectiveness of warfarin by increasing its metabolism. This interaction can lead to subtherapeutic levels of warfarin and an increased risk of thromboembolic events.
B. Gabapentin 400 mg by mouth twice daily: While gabapentin can interact with other medications, its interactions with warfarin or St. John's wort are generally not as significant as those between warfarin and St. John's wort.
C. Aspirin 81 mg by mouth daily: Aspirin has anticoagulant properties and can have interactions with warfarin. However, the interaction with St. John's wort is less pronounced compared to the interaction between warfarin and St. John's wort.
D. Atorvastatin 80 mg by mouth daily: Atorvastatin primarily affects lipid levels and has different metabolic pathways compared to warfarin. It does not have a strong interaction with St. John's wort.
E. Lisinopril 5 mg by mouth daily: Lisinopril is an ACE inhibitor and does not have significant interactions with St. John's wort or warfarin.
F. Warfarin 5 mg by mouth daily. Warfarin is an anticoagulant that requires careful monitoring due to its interactions with various substances that can either increase the risk of bleeding or decrease its effectiveness.
G. Ginger 5 mg by mouth daily: Ginger can affect platelet function but is not as significant in interaction with warfarin as St. John's wort.
H. Valerian 10 mg by mouth daily: Valerian may have mild interactions with central nervous system depressants but does not have significant interactions with warfarin or St. John's wort.
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