Complete the following sentence using the options in the drop down selection. _____ Is what the body does with the drug versus ____ which is what the drug does to the body.
Affinity
Efficacy
Biotransformation
Pharmacokinetics
Pharmacodynamics
Correct Answer : D,E
A) Affinity: Affinity refers to the strength of the interaction between a drug and its receptor. It does not describe the body's overall handling of the drug or the drug's effects on the body.
B) Efficacy: Efficacy describes the ability of a drug to produce a desired therapeutic effect. It pertains to the drug’s effectiveness once it interacts with its target but does not encompass the body's handling of the drug.
C) Biotransformation: Biotransformation is the process of drug metabolism, specifically how the body chemically alters a drug. While it is a part of pharmacokinetics, it does not cover the entire concept.
D) Pharmacokinetics: Pharmacokinetics is the term used to describe what the body does with the drug, including absorption, distribution, metabolism, and excretion. It encompasses the processes that determine the drug's concentration in the body over time.
E) Pharmacodynamics: Pharmacodynamics refers to what the drug does to the body, including the relationship between drug concentration and effect. It encompasses the mechanisms of action, including receptor interactions and therapeutic effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. An antibiotic medication that has a side effect of nausea when taken without food:
Nausea is a common side effect of many medications, including antibiotics, when taken on an empty stomach. While this side effect may cause discomfort, it is generally not a contraindication to medication administration. Patients can often manage this side effect by taking the medication with food or as advised by their healthcare provider.
B. Administering medications to a client under 4 months of age:
While administering medications to very young children requires special considerations and dosing adjustments, it is not inherently a contraindication. The key is to ensure that the medications are appropriate for the age and weight of the infant, and are prescribed and dosed correctly.
C. An antihypertensive medication given for high-blood pressure that causes orthostatic hypotension:
Orthostatic hypotension is a known side effect of some antihypertensive medications. While this side effect needs to be managed carefully, it does not represent a contraindication to the medication. Adjusting the dose or changing medications may be required to manage this side effect.
D. A medication with a Blackbox warning that the drug causes tendonitis and the patient has a history of tendonitis:
A Black Box warning is the strictest warning put in the labelling of a prescription drug by the FDA. It indicates that the drug has significant risk of serious or life-threatening adverse effects. If a medication with a Black Box warning indicates a risk of tendonitis and the patient has a history of tendonitis, this represents a contraindication, as the drug could exacerbate or trigger the condition, posing a serious risk to the patient.
Correct Answer is A
Explanation
A. Wait for at least another 30 minutes before calling to have the level drawn:
For oral medications, peak drug levels are typically drawn 1 to 2 hours after administration, depending on the medication's pharmacokinetics. Since the client took the medication only 30 minutes ago, it is premature to draw the level now. Waiting an additional 30 minutes would align with the typical peak times for oral medications, ensuring that the drug level reflects its peak concentration.
B. Schedule the level to be drawn in 8 hours:
Drawing the peak level 8 hours after administration would likely be too late, as most oral medications reach their peak concentration within 1 to 2 hours. Scheduling the level for 8 hours later may result in an inaccurate measurement of the peak drug level, leading to potentially misleading clinical information.
C. Call the lab to have the medication level drawn immediately:
Drawing the level immediately after 30 minutes may not provide an accurate representation of the peak drug level. Oral medications generally reach peak levels later, and an early draw could result in a falsely low measurement that does not reflect the drug's maximum concentration.
D. Arrange for the level to be drawn tomorrow since the peak time has passed:
The peak time has not passed, as the medication was only administered 30 minutes ago. Drawing the level tomorrow would be far too late to assess the peak concentration accurately, which is essential for evaluating the effectiveness and safety of the medication.
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