The nurse is caring for a client who has prostate cancer. Which of the following manifestations does the nurse attribute to the advancing disease process?

Choice A reason:
Immunoglobulin G (IgG) is the most common type of antibody found in blood circulation and is involved in the body's immune response to fight infections. However, IgG is not typically associated with allergic reactions, which are immediate hypersensitivity reactions.

Choice B reason:
Immunoglobulin A (IgA) plays a critical role in mucosal immunity and is found in high concentrations in the mucous membranes, particularly those lining the respiratory passages and gastrointestinal tract. Like IgG, IgA is not primarily responsible for the allergic response seen in conditions such as seasonal allergies.

Choice C reason:
Immunoglobulin M (IgM) is usually the first antibody produced by the immune system when it detects an infection. IgM antibodies are larger and are involved in the primary immune response but are not the antibodies that mediate typical allergic reactions.

Choice D reason:
Immunoglobulin E (IgE) is the antibody that plays a central role in the pathophysiology of allergic diseases, including seasonal allergies. IgE antibodies are produced as a response to allergens and are responsible for the symptoms of an allergic reaction. An elevation in IgE levels typically indicates a positive result for an allergy test such as RAST.

Choice A reason:
A BUN level of 8 mg/dL and a creatinine level of 0.7 mg/dL are within normal ranges for a healthy individual without kidney disease. In chronic kidney disease (CKD), we would expect these values to be elevated due to the kidneys' reduced ability to filter waste products from the blood.

Choice B reason:
A BUN level of 45 mg/dL and a creatinine level of 8 mg/dL are significantly higher than the normal range, which is consistent with impaired kidney function seen in CKD. These elevated levels indicate that the kidneys are not effectively filtering urea and creatinine from the blood, leading to their accumulation.

Choice C reason:
A BUN level of 23 mg/dL and a creatinine level of 1.0 mg/dL could be seen in the early stages of CKD. While the creatinine level is within the normal range, the BUN level is slightly elevated, which may suggest a decline in kidney function.

Choice D reason:
A BUN level of 10 mg/dL and a creatinine level of 0.3 mg/dL are both below the normal range. This is an unlikely finding for a patient with CKD, as kidney impairment typically leads to increased levels of these substances in the blood.