The nurse is caring for a client being treated for depression. The nurse understands that a selective serotonin reuptake inhibitor (SSRI) would be chosen as a first-line treatment option over a tricyclic antidepressant (TCA) for which of the following reasons?

To help prevent sexual dysfunction

To avoid weight gain and other gastrointestinal (GI) eﬀects

To prevent the risk of serotonin syndrome

To reduce the risk of suicide with overdose

Answer and Explanation

The Correct Answer is D

A selective serotonin reuptake inhibitor (SSRI) would be chosen as a first-line treatment option over a tricyclic antidepressant (TCA) for several reasons, including reducing the risk of suicide with overdose ³. TCAs have a higher potential for serious or fatal toxicity when taken in large amounts compared to SSRIs ³.
Option A is incorrect because SSRIs can cause sexual dysfunction as a side effect.
Option B is incorrect because both SSRIs and TCAs can cause weight gain and gastrointestinal (GI) eﬀects.
Option C is incorrect because SSRIs can increase the risk of serotonin syndrome when taken with other medications that affect serotonin levels.

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Correct Answer is C

Explanation

An accidental administration of a dose greater than recommended can result in toxicity. This means that the medication reaches harmful levels in the body and can cause damage to organs or other adverse effects.
Option A is incorrect because an overdose is more likely to increase side effects rather than decrease them.
Option B is incorrect because a lowered therapeutic threshold means that a lower dose of medication is needed to achieve the desired eﬀect, which is not related to an overdose.
Option D is incorrect because an overdose can increase the eﬀectiveness of the medication to dangerous levels, rather than decrease it.

A. 50 mg B. 200 mg C. 100 mg D. 400 mg

Correct Answer is C

Explanation

A half-life is the time it takes for the concentration of a drug in the body to decrease by half. In this case, the medication has an 8-hour half-life, so after 8 hours, the concentration of the medication in the client's body would be reduced to 400mg (half of the initial dose of 800mg). After another 8 hours (16 hours total), the concentration would be reduced to 200mg. After another 8 hours (24 hours total), the concentration would be reduced to 100mg.

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The nurse is caring for a client being treated for depression. The nurse understands that a selective serotonin reuptake inhibitor (SSRI) would be chosen as a first-line treatment option over a tricyclic antidepressant (TCA) for which of the following reasons?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is aware that an accidental administration of a dose greater than recommended is most likely to result in what negative consequence?

Correct Answer is C

Explanation

The nurse has given 800mg of a medication that has an 8-hour half-life. How much of the medication will remain in the client's body 24 hours after administration if no additional medication is given?

Correct Answer is C

Explanation

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