Which statement made by the nurse explains the rationale for the use of donepezil for clients diagnosed with Alzheimer's dementia?
Donepezil increases the availability of acetylcholine at cholinergic synapses.
Donepezil decreases acetylcholine in the periphery to increase movement.
Donepezil delays transmission of acetylcholine at the neuronal junction.
Donepezil works to bind the dopamine at neuron receptor sites to increase ability.
The Correct Answer is A
Donepezil is a medication used to treat Alzheimer's dementia. Its main mechanism of action is the inhibition of the acetylcholinesterase enzyme in the brain ¹. This increases the availability of acetylcholine at cholinergic synapses ⁵, which can improve cognition and function in clients with Alzheimer's dementia ¹.
Option B is incorrect because donepezil does not decrease acetylcholine in the periphery to increase movement.
Option C is incorrect because donepezil does not delay the transmission of acetylcholine at the neuronal junction.
Option D is incorrect because donepezil does not bind dopamine at neuron receptor sites to increase ability.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
It is important for the nurse to understand why the client is refusing to take the medication. There may be underlying reasons such as side effects, fear, or misunderstanding about the medication. By investigating and addressing these concerns, the nurse can help the client make an informed decision about their treatment.
Option A may not address the underlying reasons for noncompliance and could be perceived as confrontational.
Option C may be appropriate after understanding the reasons for noncompliance and discussing them with the provider.
Option D may also be appropriate in some cases, but it is important to first understand the reasons for noncompliance before involving a social worker.
Correct Answer is D
Explanation
Memantine is a medication used to treat moderate-to-severe Alzheimer's disease ¹². It works by reducing the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease ¹. While memantine can help slow the progression of Alzheimer's disease, it is not a cure and may not improve the condition ².
Option A is not correct because constipation is a common side effect of memantine ².
Option B is not correct because memantine is approved for moderate-to-severe Alzheimer's disease ¹².
Option C is not correct because memantine does regulate the effects of glutamate ³.
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