The healthcare provider has ordered 1000 mL of 0.9% sodium chloride to be administered intravenously over 5 hours. The drop factor on the tubing is 15 drops/mL. How many milliliters per hour will you administer and how many drops per minute?

A) Stool softener:
Stool softeners, such as docusate sodium, work by adding moisture to the stool, making it softer and easier to pass. They do not directly stimulate bowel movements or peristalsis through irritation of the bowel lining.

B) Saline/osmotic laxative:
Saline or osmotic laxatives, such as magnesium hydroxide (milk of magnesia) and polyethylene glycol (PEG), work by drawing water into the intestines, which softens the stool and increases bowel motility. They do not primarily act by irritating the bowel lining.

C) Stimulant laxative.
Stimulant laxatives work by directly stimulating the nerves in the intestines, which increases the rhythmic contractions of the intestines (peristalsis) and promotes bowel movements. These medications irritate the bowel lining, leading to increased motility and expulsion of stool. Examples of stimulant laxatives include bisacodyl and senna.

D) Bulk-forming laxative:
Bulk-forming laxatives, such as psyllium and methylcellulose, work by increasing the bulk and water content of the stool, which stimulates bowel movements. They do not directly irritate the bowel lining to promote peristalsis. Instead, they absorb water and swell in the intestines, creating a larger, softer stool that is easier to pass.

A) Sedation:
Sedation is not an adverse effect commonly associated with oxymetazoline nasal spray. Oxymetazoline works by constricting blood vessels in the nasal passages to relieve congestion and does not typically cause sedation.

B) Constipation:
Constipation is not an adverse effect associated with oxymetazoline nasal spray. Constipation is more commonly associated with medications that affect the gastrointestinal system, such as opioid analgesics or certain anticholinergic medications.

C) Productive cough:
Productive cough is not an adverse effect commonly associated with oxymetazoline nasal spray. Productive cough refers to a cough that produces mucus or phlegm and is more often associated with respiratory infections or chronic respiratory conditions.

D) Nasal congestion.
Oxymetazoline (Afrin) is a nasal decongestant spray commonly used for the temporary relief of nasal congestion associated with allergic rhinitis or the common cold. However, if oxymetazoline nasal spray is used for more than 3 to 5 consecutive days, it can lead to rebound congestion, also known as rhinitis medicamentosa. Rebound congestion occurs when the nasal mucosa becomes dependent on the medication for vasoconstriction, and upon discontinuation, nasal congestion worsens. Therefore, prolonged use of oxymetazoline nasal spray can result in a worsening of nasal congestion as an adverse effect.