The drug nalbuphine is an agonist-antagonist (partial agonist). The nurse understands that which is a characteristic of partial agonists?

They have a lower dependency potential than agonists.

They have a higher potency than agonists

They have anti-inflammatory effects.

They are given to reverse the effects of opiates

Answer and Explanation

The Correct Answer is A

A. Partial agonists like nalbuphine have a lower dependency potential than full agonists. This means they are less likely to lead to physical dependence or tolerance when used for pain
management.

B. Partial agonists do not necessarily have a higher potency than agonists. Potency refers to the dose of a drug required to produce a specific effect, which can vary among different drugs regardless of their classification as agonists or partial agonists.
C. Partial agonists like nalbuphine are not typically used for their anti-inflammatory effects.

They are primarily used for pain management.

D. Partial agonists like nalbuphine are not typically used to reverse the effects of opiates. They may be used in certain situations to manage opioid-induced side effects or in cases of opioid overdose, but their primary indication is for pain management.

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Correct Answer is D

Explanation

A. Minimize the amount of fluid taken while on this drug: Increasing fluid intake is actually recommended to manage potential constipation, another common side effect of anticholinergic medications.
B. Discontinue the medication if adverse effects occur: Discontinuing medication without consulting a healthcare provider is not advisable. Patients should be educated to report any adverse effects to their healthcare provider for appropriate management.
C. Take the medication on an empty stomach to enhance absorption: Benztropine is typically taken with food to minimize gastrointestinal side effects. Taking it on an empty stomach may increase the risk of nausea or stomach upset.
D. Use artificial saliva, sugarless gum, or hard candy to counteract dry mouth: Anticholinergic medications such as benztropine commonly cause dry mouth as a side effect. Stimulating saliva production with these measures can help alleviate dry mouth symptoms.

A. Oral contraceptives B. Antihistamines C. Warfarin D. Opioids E. Diuretics

Correct Answer is ["A","D","E"]

Explanation

A. Oral contraceptives: Phenobarbital can decrease the effectiveness of oral contraceptives, increasing the risk of contraceptive failure and unintended pregnancy.
B. Antihistamines: While phenobarbital can induce hepatic enzymes, leading to increased

metabolism of some antihistamines, this interaction is less clinically significant compared to the interactions with oral contraceptives, opioids, and diuretics.
C. Warfarin: Phenobarbital can induce the metabolism of warfarin, potentially reducing its anticoagulant effects and necessitating closer monitoring of international normalized ratio (INR) levels.
D. Opioids: Phenobarbital can increase the metabolism of opioids, leading to reduced analgesic effects and potentially causing inadequate pain control.

E. Diuretics: Phenobarbital can accelerate the metabolism of diuretics, potentially reducing their efficacy and necessitating adjustments in dosage or monitoring of electrolyte levels.

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The drug nalbuphine is an agonist-antagonist (partial agonist). The nurse understands that which is a characteristic of partial agonists?

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Naxlex Comprehensive Predictor Exams

When a patient is taking an anticholinergic such as benztropine as part of the treatment for Parkinson's disease, the nurse should include which information in the teaching plan?

Correct Answer is D

Explanation

The barbiturate phenobarbital is prescribed for a patient with epilepsy. While assessing the patient's current medications, the nurse recognizes that interactions may occur with which drugs? (Select all that apply.)

Correct Answer is ["A","D","E"]

Explanation

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