The drug nalbuphine is an agonist-antagonist (partial agonist). The nurse understands that which is a characteristic of partial agonists?
They have a lower dependency potential than agonists.
They have a higher potency than agonists
They have anti-inflammatory effects.
They are given to reverse the effects of opiates
The Correct Answer is A
A. Partial agonists like nalbuphine have a lower dependency potential than full agonists. This means they are less likely to lead to physical dependence or tolerance when used for pain
management.
B. Partial agonists do not necessarily have a higher potency than agonists. Potency refers to the dose of a drug required to produce a specific effect, which can vary among different drugs regardless of their classification as agonists or partial agonists.
C. Partial agonists like nalbuphine are not typically used for their anti-inflammatory effects.
They are primarily used for pain management.
D. Partial agonists like nalbuphine are not typically used to reverse the effects of opiates. They may be used in certain situations to manage opioid-induced side effects or in cases of opioid overdose, but their primary indication is for pain management.
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Related Questions
Correct Answer is A
Explanation
A. Carbidopa prevents the breakdown of levodopa in the periphery, specifically in the gastrointestinal tract and peripheral tissues, allowing more levodopa to reach the brain and be converted to dopamine. This enhances the effectiveness of levodopa therapy in managing the symptoms of Parkinson's disease.
B. Carbidopa is not the biologic precursor of dopamine. It is a peripheral decarboxylase inhibitor that does not cross the blood-brain barrier.
C. Carbidopa does not directly allow for larger doses of levodopa to be given. However, by
inhibiting the peripheral breakdown of levodopa, it enhances the availability of levodopa to the central nervous system, potentially improving therapeutic efficacy.
D. While levodopa-carbidopa combination therapy may have fewer drug-food interactions compared to levodopa alone, the primary reason for combining these medications is to enhance the effectiveness of levodopa by preventing its peripheral breakdown.
Correct Answer is B
Explanation
A. A lithium level of 0.9 mEq/L falls within the therapeutic range for lithium, so it is not too low.
B. A lithium level of 0.9 mEq/L is within the therapeutic range for lithium maintenance therapy, which typically ranges from 0.6 to 1.2 mEq/L. Therefore, it is considered therapeutic.
C. Lithium is commonly monitored with blood levels to ensure therapeutic efficacy and to prevent toxicity.
D. A lithium level of 0.9 mEq/L is not too high; it is within the therapeutic range.
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