The barbiturate phenobarbital is prescribed for a patient with epilepsy. While assessing the patient's current medications, the nurse recognizes that interactions may occur with which drugs? (Select all that apply.)
Oral contraceptives
Antihistamines
Warfarin
Opioids
Diuretics
Correct Answer : A,D,E
A. Oral contraceptives: Phenobarbital can decrease the effectiveness of oral contraceptives, increasing the risk of contraceptive failure and unintended pregnancy.
B. Antihistamines: While phenobarbital can induce hepatic enzymes, leading to increased
metabolism of some antihistamines, this interaction is less clinically significant compared to the interactions with oral contraceptives, opioids, and diuretics.
C. Warfarin: Phenobarbital can induce the metabolism of warfarin, potentially reducing its anticoagulant effects and necessitating closer monitoring of international normalized ratio (INR) levels.
D. Opioids: Phenobarbital can increase the metabolism of opioids, leading to reduced analgesic effects and potentially causing inadequate pain control.
E. Diuretics: Phenobarbital can accelerate the metabolism of diuretics, potentially reducing their efficacy and necessitating adjustments in dosage or monitoring of electrolyte levels.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Getting up slowly from a sitting or lying position is an important aspect of patient education for individuals taking tamsulosin, as this medication can cause orthostatic hypotension, leading to dizziness or fainting upon standing up quickly.
B. Tamsulosin is often taken once daily, approximately 30 minutes after the same meal each day, typically breakfast or the first meal of the day. Taking it with breakfast is not a requirement for
its efficacy.
C. There is no need to restrict fluids while on tamsulosin therapy. In fact, adequate hydration is generally encouraged.
D. Tamsulosin is not typically associated with causing hypertension. Instead, it is more commonly associated with hypotension, especially orthostatic hypotension.
Correct Answer is A
Explanation
A. Menstrual cramps: Feverfew is commonly used as an herbal remedy for menstrual cramps and migraines due to its purported anti-inflammatory and smooth muscle relaxant properties.
B. Constipation: Feverfew is not typically used to treat constipation.
C. Muscle aches: While feverfew may have some anti-inflammatory properties, it is not commonly used specifically for muscle aches.
D. Incision pain after surgery: Feverfew is not typically used to manage post-surgical pain.
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