A nurse is preparing to administer amantadine 150 mg PO every 12 hr. Available is amantadine 50 mg/5 mL syrup. How many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

A. Oral contraceptives: Phenobarbital can decrease the effectiveness of oral contraceptives, increasing the risk of contraceptive failure and unintended pregnancy.
B. Antihistamines: While phenobarbital can induce hepatic enzymes, leading to increased

metabolism of some antihistamines, this interaction is less clinically significant compared to the interactions with oral contraceptives, opioids, and diuretics.
C. Warfarin: Phenobarbital can induce the metabolism of warfarin, potentially reducing its anticoagulant effects and necessitating closer monitoring of international normalized ratio (INR) levels.
D. Opioids: Phenobarbital can increase the metabolism of opioids, leading to reduced analgesic effects and potentially causing inadequate pain control.

E. Diuretics: Phenobarbital can accelerate the metabolism of diuretics, potentially reducing their efficacy and necessitating adjustments in dosage or monitoring of electrolyte levels.

A. Myoclonic seizures are characterized by sudden, brief muscle jerks or twitches. These

movements are usually more pronounced and may involve multiple muscle groups compared to the described behavior, which involves a brief pause in activity without muscle jerks.

B. Absence seizures are characterized by brief episodes of staring or blanking out, often lasting for a few seconds. During an absence seizure, the child may appear to be staring into space, unaware of their surroundings. After the seizure, the child typically resumes their previous
activity without any memory of the event.

C. Status epilepticus refers to a prolonged seizure or a series of seizures without full recovery of consciousness between seizures. This condition is a medical emergency and presents with continuous or recurrent seizures without regaining consciousness.
D. Tonic-clonic seizures involve a sequence of tonic (stiffening) and clonic (jerking) phases, often accompanied by loss of consciousness and sometimes preceded by an aura. The described behavior does not fit the pattern of a tonic-clonic seizure, which typically involves more noticeable motor activity and loss of consciousness.