(Select All That Apply): A nurse is teaching a group of nursing students about the diagnostic criteria for major depressive disorder (MDD) according to DSM-5. Which of the following are part of the diagnostic criteria? Select all that apply.

Choice A rationale:

Genetic predisposition refers to a person's susceptibility to certain conditions based on their genetic makeup. While genetics can play a role in predisposing someone to depression, it is not considered a psychosocial factor. Genetic factors are biological in nature and do not directly involve social and psychological influences.

Choice B rationale:

The role of stress and life events is a significant psychosocial factor related to depression. Stressful life events, such as trauma, loss, or major life changes, can trigger or exacerbate depressive episodes in susceptible individuals. The interaction between these external stressors and an individual's psychological responses is a key aspect of psychosocial factors.

Choice C rationale:

Interpersonal relationships are another important psychosocial factor linked to depression. Poor interpersonal relationships, social isolation, and conflicts with friends or family can contribute to feelings of loneliness and despair, increasing the risk of developing depression.

Choice D rationale:

Cognitive factors, including negative thought patterns and distorted thinking, are considered psychosocial contributors to depression. Cognitive theories of depression emphasize how an individual's thought processes, self-perception, and interpretation of events can influence their emotional state. Dysfunctional thought patterns, such as excessive self-criticism or hopelessness, can contribute to the development and maintenance of depressive symptoms.

Choice E rationale:

Neurotransmitter imbalances are not psychosocial factors. They are more related to the biological underpinnings of depression rather than the social and psychological influences explored in psychosocial factors.

Choice A rationale:

Bipolar disorder involves both depressive episodes and manic episodes. The client in question denies any history of manic episodes, making bipolar disorder less likely as a diagnosis. Manic episodes are characterized by elevated mood, increased energy, impulsivity, and risky behavior.

Choice B rationale:

Dysthymia, also known as persistent depressive disorder, involves chronic feelings of sadness and a lack of interest or pleasure in activities. It is a milder form of depression that persists for at least two years in adults. The client's persistent feelings of sadness align more closely with the criteria for dysthymia.

Choice C rationale:

Substance-induced mood disorder occurs when the client's mood disturbances are a direct result of substance use or withdrawal. Since there is no mention of substance use or withdrawal in the client's history, this choice is less relevant to the scenario.

Choice D rationale:

Adjustment disorder is characterized by the development of emotional or behavioral symptoms in response to an identifiable stressor, and these symptoms typically resolve within six months of the stressor's resolution. In the scenario, there is no indication of a recent stressor, and the client's symptoms seem to be chronic rather than time-limited, making adjustment disorder less likely.