(Select All That Apply): A nurse is teaching a group of nursing students about the diagnostic criteria for major depressive disorder (MDD) according to DSM-5. Which of the following are part of the diagnostic criteria? Select all that apply.

Choice A rationale:

Signs of normal bereavement. Bereavement refers to the period of grief and mourning after the loss of a loved one. While fatigue and feelings of worthlessness can be experienced during bereavement, difficulty concentrating is not a typical sign. Additionally, bereavement-related symptoms typically improve over time as the individual processes their loss. The combination of extreme fatigue, difficulty concentrating, and thoughts of worthlessness suggests a more severe and persistent condition than normal bereavement.

Choice B rationale:

Symptoms of bipolar disorder. Bipolar disorder is characterized by alternating episodes of depression and mania (or hypomania). The client's symptoms of extreme fatigue, difficulty concentrating, and thoughts of worthlessness are primarily indicative of a depressive episode, which is only one aspect of bipolar disorder. Bipolar disorder requires the presence of manic or hypomanic episodes, which are not mentioned in the client's presentation.

Choice C rationale:

Indicators of substance-induced mood disorder. Substance-induced mood disorder occurs as a result of substance use or withdrawal and involves changes in mood and affect. While substances can lead to symptoms similar to depression, the combination of symptoms presented by the client (fatigue, difficulty concentrating, thoughts of worthlessness) is more indicative of a primary mood disorder rather than one directly caused by substance use.

Choice D rationale:

Criteria for diagnosing MDD according to DSM-5. The client's symptoms of extreme fatigue, difficulty concentrating, and thoughts of worthlessness align with the criteria for Major Depressive Disorder (MDD) as defined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). These criteria include the presence of specific symptoms for a specified duration, causing significant impairment in functioning. The symptoms should not be better explained by other conditions or substances. In this case, the client's presentation closely matches the criteria for diagnosing MDD.

Choice A rationale:

"MDD is less severe than dysthymia but lasts for at least 2 years." This statement is incorrect. Major Depressive Disorder (MDD) is characterized by the presence of a major depressive episode, which can be severe and persistent, lasting for at least two weeks. Dysthymia, on the other hand, is a chronic but milder form of depression that lasts for at least two years, not MDD.

Choice B rationale:

"Dysthymia is characterized by alternating episodes of mania and depression." This statement is incorrect. Dysthymia is a chronic mood disorder characterized by a persistent low mood and other depressive symptoms. It does not involve alternating episodes of mania and depression. Alternating episodes of mania and depression are characteristic of bipolar disorder, not dysthymia.

Choice C rationale:

"Unlike MDD, dysthymia does not impair social or occupational functioning." This statement is incorrect. Both Major Depressive Disorder (MDD) and dysthymia can significantly impair social, occupational, and other areas of functioning. In fact, dysthymia's chronic nature often leads to long-term impairment in various aspects of an individual's life, similar to MDD.

Choice D rationale:

"Dysthymia is chronic and lasts for at least 2 years, but is less severe than MDD." This statement is accurate. Dysthymia is a chronic form of depression that persists for at least two years. While it may not exhibit the same level of severity as a major depressive episode, its long-term nature can still have a substantial impact on an individual's quality of life. This distinguishes it from MDD, which can have episodic occurrences.