A nurse is reviewing the medication list for a client who has a new diagnosis of type 2 diabetes mellitus. The nurse should recognize which of the following medications can cause glucose intolerance?

Dextromethorphan

Prednisone

Atorvastatin

Cimetidine

Answer and Explanation

The Correct Answer is B

Choice A reason: Dextromethorphan is a cough suppressant that does not affect blood glucose levels. It is safe to use for clients with diabetes.

Choice B reason: Prednisone is a corticosteroid that can cause glucose intolerance by increasing glucose production and decreasing insulin sensitivity. It can worsen hyperglycemia and increase the risk of diabetic complications.

Choice C reason: Atorvastatin is a statin that lowers cholesterol levels and reduces the risk of cardiovascular disease. It does not cause glucose intolerance and may have a beneficial effect on glycemic control.

Choice D reason: Cimetidine is a histamine-2 receptor antagonist that reduces stomach acid production and treats ulcers and gastroesophageal reflux disease. It does not cause glucose intolerance and has no significant interaction with diabetes medications.

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Correct Answer is A

Explanation

The correct answer is a. Alcohol.

Choice A: Alcohol

Reason: Alcohol can significantly affect blood glucose levels in patients taking glimepiride. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) can occur depending on the amount and frequency of alcohol consumption. Alcohol can enhance the blood sugar-lowering effect of glimepiride, leading to a dangerous drop in blood sugar levels, known as hypoglycemia. Symptoms of hypoglycemia include dizziness, confusion, weakness, and in severe cases, loss of consciousness. Therefore, it is advised to avoid alcohol while taking glimepiride.

Choice B: Milk

Reason: There are no known interactions between glimepiride and milk. Milk does not affect the absorption or efficacy of glimepiride. Therefore, it is generally safe to consume milk while taking this medication.

Choice C: Grapefruit juice

Reason: Grapefruit juice might theoretically increase the levels of drugs metabolized by CYP2C9, including glimepiride, due to its potential to inhibit CYP2C9 enzymes. However, this interaction has not been reported in humans and is considered unlikely to have a significant clinical impact. Therefore, grapefruit juice is not a major concern for patients taking glimepiride.

Choice D: Coffee

Reason: Coffee and other caffeinated beverages may increase blood sugar levels, which can counteract the effects of glimepiride. However, this interaction is not as significant as the interaction with alcohol. It is generally advised to monitor blood sugar levels and consume coffee in moderation while taking glimepiride.

A. Incidence of nausea B. Levels of triglycerides C. Risk for thrombosis D. Tendency to bleed during menstruation

Correct Answer is C

Explanation

Choice A reason: This is incorrect because nausea is not a common or serious adverse effect of estrogen therapy. However, the patient should take the estrogen with food or milk to prevent stomach upset.

Choice B reason: This is incorrect because triglycerides are not affected by estrogen therapy. However, the patient should monitor their cholesterol and blood pressure levels regularly and follow a healthy diet and exercise regimen.

Choice C reason: This is correct because smoking and estrogen therapy are both risk factors for thrombosis, which is the formation of blood clots in the blood vessels. The patient should stop smoking and report any signs of thrombosis, such as leg pain, swelling, redness, or warmth, to the provider.

Choice D reason: This is incorrect because bleeding during menstruation is not increased by estrogen therapy. However, the patient should report any abnormal vaginal bleeding, such as spotting, heavy bleeding, or prolonged bleeding, to the provider.

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A nurse is reviewing the medication list for a client who has a new diagnosis of type 2 diabetes mellitus. The nurse should recognize which of the following medications can cause glucose intolerance?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is teaching a client who has diabetes mellitus and a new prescription for glimepiride. The nurse should teach the client to avoid which of the following drinks while taking this medication?

Correct Answer is A

Explanation

During a follow-up visit, a patient who has been on estrogen therapy admits that she has continued to smoke cigarettes. The nurse will remind the patient that smoking while on estrogen may lead to increased:

Correct Answer is C

Explanation

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