A nurse is providing teaching for a client who has diabetes and a new prescription for insulin glargine. Which of the following instructions should the nurse provide regarding this type of insulin?

Choice A reason: This is incorrect because insulin glargine has a longer duration than 6 to 10 hr. Insulin glargine is a long-acting insulin that provides a steady and continuous level of insulin in the blood. It is usually given once daily at the same time.

Choice B reason: This is incorrect because insulin glargine has a longer duration than 3 to 6 hr. Insulin glargine is not a short-acting or rapid-acting insulin that peaks quickly and lasts for a few hours. It is a long-acting insulin that does not have a peak and lasts for up to 24 hr.

Choice C reason: This is incorrect because insulin glargine has a longer duration than 16 to 24 hr. Insulin glargine is a long-acting insulin that can last for up to 24 hr, but not more than that. It is not an ultra-long-acting insulin that can last for more than 24 hr.

Choice D reason: This is correct because insulin glargine has a duration of 18 to 24 hr. Insulin glargine is a long-acting insulin that provides a steady and continuous level of insulin in the blood. It is usually given once daily at the same time.

Choice A reason: This is incorrect because lispro insulin is a rapid-acting insulin that does not need to be administered with another type of insulin. However, the patient may need a long-acting or intermediate-acting insulin to provide basal coverage throughout the day.

Choice B reason: This is incorrect because lispro insulin has a peak action of 30 to 90 min after the injection, which means that the patient is at the highest risk of hypoglycemia during this time. The nurse should assess for hypoglycemia more frequently than 4 hr after the injection.

Choice C reason: This is correct because lispro insulin has a fast onset of action of 15 to 30 min after the injection, which means that the patient should eat a meal within 15 min of the injection to prevent hypoglycemia.

Choice D reason: This is incorrect because polyuria is a sign of hyperglycemia, not hypoglycemia. The nurse should monitor for polyuria before the insulin injection, as it may indicate that the patient's blood glucose level is high.