The nurse is planning an educational program on sildenafil to a group of older male clients. Which of the following information should the nurse include in the educational program?
Consume a high-fat meal to increase the medication absorption.
Take the medication 2 hours prior to sexual activity.
Swallow the medication with grapefruit juice to improve the action.
Avoid ingestion of the medication with nitrates because it causes hypotension.
The Correct Answer is D
Choice A reason: Consuming a high-fat meal does not increase the medication absorption, but rather delays it. A high-fat meal can reduce the peak plasma concentration and prolong the onset of action of sildenafil.
Choice B reason: Taking the medication 2 hours prior to sexual activity is not the optimal timing, as sildenafil has a half-life of about 4 hours and reaches its peak effect within 30 to 120 minutes. The recommended dose is 50 mg taken as needed, approximately 1 hour before sexual activity.
Choice C reason: Swallowing the medication with grapefruit juice does not improve the action, but rather inhibits it. Grapefruit juice can interfere with the metabolism of sildenafil and increase its plasma concentration and side effects.
Choice D reason: Avoiding ingestion of the medication with nitrates is the correct information, as it can cause a severe and potentially fatal drop in blood pressure. Nitrates are drugs used to treat angina and heart failure, and they can interact with sildenafil to cause vasodilation and hypotension.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Venous thromboembolism is a contraindication for taking SERMs. SERMs are drugs that act like estrogen in some tissues and block estrogen in others. They can help prevent bone loss and fractures in postmenopausal women, but they can also increase the risk of blood clots in the veins, such as deep vein thrombosis and pulmonary embolism. Therefore, women who have a history of or are at high risk for venous thromboembolism should not take SERMs.
Choice B reason: Breast cancer is not a contraindication for taking SERMs. In fact, some SERMs, such as tamoxifen and raloxifene, are used to treat or prevent breast cancer in women who have estrogen receptor-positive tumors. These SERMs block the effects of estrogen in the breast tissue and reduce the growth of cancer cells.
Choice C reason: Hypocalcemia is not a contraindication for taking SERMs. Hypocalcemia is a low level of calcium in the blood. SERMs do not affect calcium levels directly, but they can help prevent calcium loss from the bones by mimicking the effects of estrogen in the bone tissue. However, women who take SERMs should also take adequate calcium and vitamin D supplements to maintain bone health.
Choice D reason: Stress fractures are not a contraindication for taking SERMs. Stress fractures are small cracks in the bones that result from repeated stress or overuse. SERMs can help prevent stress fractures by strengthening the bones and reducing the risk of osteoporosis. However, women who take SERMs should also avoid excessive or inappropriate physical activity that can cause stress fractures.
Correct Answer is B
Explanation
Choice A reason: This is incorrect because the client should avoid live vaccines while taking prednisone, as it can suppress the immune system and increase the risk of infection.
Choice B reason: This is correct because prednisone can cause hypokalemia (low potassium levels) and bananas are a good source of potassium. The client should monitor their potassium levels and eat foods rich in potassium while taking prednisone.
Choice C reason: This is incorrect because the client should avoid nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin while taking prednisone, as they can increase the risk of gastrointestinal bleeding and ulceration.
Choice D reason: This is incorrect because a sore throat is not a common side effect of prednisone. However, the client should report any signs of infection, such as fever, sore throat, or cough, to the provider, as prednisone can mask the symptoms of infection.
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