The nurse is planning an educational program on sildenafil to a group of older male clients. Which of the following information should the nurse include in the educational program?

Consume a high-fat meal to increase the medication absorption.

Take the medication 2 hours prior to sexual activity.

Swallow the medication with grapefruit juice to improve the action.

Avoid ingestion of the medication with nitrates because it causes hypotension.

Answer and Explanation

The Correct Answer is D

Choice A reason: Consuming a high-fat meal does not increase the medication absorption, but rather delays it. A high-fat meal can reduce the peak plasma concentration and prolong the onset of action of sildenafil.

Choice B reason: Taking the medication 2 hours prior to sexual activity is not the optimal timing, as sildenafil has a half-life of about 4 hours and reaches its peak effect within 30 to 120 minutes. The recommended dose is 50 mg taken as needed, approximately 1 hour before sexual activity.

Choice C reason: Swallowing the medication with grapefruit juice does not improve the action, but rather inhibits it. Grapefruit juice can interfere with the metabolism of sildenafil and increase its plasma concentration and side effects.

Choice D reason: Avoiding ingestion of the medication with nitrates is the correct information, as it can cause a severe and potentially fatal drop in blood pressure. Nitrates are drugs used to treat angina and heart failure, and they can interact with sildenafil to cause vasodilation and hypotension.

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Correct Answer is B

Explanation

Choice A reason: Antibiotics are not likely to interact with corticosteroids, unless they are aminoglycosides, which can increase the risk of hypokalemia. However, most antibiotics do not affect the metabolism or efficacy of corticosteroids.

Choice B reason: Nonsteroidal anti-inflammatory drugs (NSAIDs) can interact with corticosteroids, as they both have anti-inflammatory and immunosuppressive effects. This can increase the risk of gastrointestinal bleeding, ulceration, and perforation. Therefore, the nurse should monitor the patient for signs of bleeding and advise the patient to avoid taking NSAIDs with corticosteroids.

Choice C reason: Opioid analgesics are not likely to interact with corticosteroids, unless they are codeine, which can decrease the clearance of corticosteroids. However, most opioid analgesics do not affect the metabolism or efficacy of corticosteroids.

Choice D reason: Antidepressants are not likely to interact with corticosteroids, unless they are monoamine oxidase inhibitors (MAOIs), which can increase the risk of hypertension and hypertensive crisis. However, most antidepressants do not affect the metabolism or efficacy of corticosteroids.

A. Hypotension B. Muscle weakness C. Osteoporosis D. Delayed wound healing

Correct Answer is D

Explanation

Choice A reason: This is incorrect because hypotension is not a common effect of long-term corticosteroid therapy. Corticosteroids can cause fluid retention and sodium retention, which can lead to hypertension, not hypotension.

Choice B reason: This is incorrect because muscle weakness is not the most impactful effect of long-term corticosteroid therapy on the patient's recovery. Corticosteroids can cause muscle wasting and loss of muscle mass, which can affect the patient's mobility and strength, but not as much as delayed wound healing.

Choice C reason: This is incorrect because osteoporosis is not the most impactful effect of long-term corticosteroid therapy on the patient's recovery. Corticosteroids can cause bone loss and increased risk of fractures, which can affect the patient's bone health and stability, but not as much as delayed wound healing.

Choice D reason: This is correct because delayed wound healing is the most impactful effect of long-term corticosteroid therapy on the patient's recovery. Corticosteroids can impair the inflammatory response and the immune system, which can slow down the healing process and increase the risk of infection. This can affect the patient's recovery time and quality.

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The nurse is planning an educational program on sildenafil to a group of older male clients. Which of the following information should the nurse include in the educational program?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

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Correct Answer is B

Explanation

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Correct Answer is D

Explanation

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