The nurse is preparing to administer the contraceptive form of medroxyprogesterone. What route is appropriate?

Choice A reason: Consuming a high-fat meal does not increase the medication absorption, but rather delays it. A high-fat meal can reduce the peak plasma concentration and prolong the onset of action of sildenafil.

Choice B reason: Taking the medication 2 hours prior to sexual activity is not the optimal timing, as sildenafil has a half-life of about 4 hours and reaches its peak effect within 30 to 120 minutes. The recommended dose is 50 mg taken as needed, approximately 1 hour before sexual activity.

Choice C reason: Swallowing the medication with grapefruit juice does not improve the action, but rather inhibits it. Grapefruit juice can interfere with the metabolism of sildenafil and increase its plasma concentration and side effects.

Choice D reason: Avoiding ingestion of the medication with nitrates is the correct information, as it can cause a severe and potentially fatal drop in blood pressure. Nitrates are drugs used to treat angina and heart failure, and they can interact with sildenafil to cause vasodilation and hypotension.

Choice A reason: You should avoid alcohol intake while taking codeine, not limit it to 12 ounces daily. Alcohol can increase the risk of side effects such as drowsiness, dizziness, and respiratory depression.

Choice B reason: You should not expect to experience diarrhea while taking codeine. Codeine can cause constipation, not diarrhea. You should increase your fluid and fiber intake and use laxatives as prescribed to prevent constipation.

Choice C reason: You should not take the medication on an empty stomach to prevent nausea. Codeine can cause nausea and vomiting, especially on an empty stomach. You should take the medication with food or milk to reduce nausea.

Choice D reason: You should change positions slowly while taking codeine. Codeine can cause orthostatic hypotension, which is a sudden drop in blood pressure when you stand up. This can cause dizziness, fainting, and falls. You should change positions slowly and use caution when walking or climbing stairs.