A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil. He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?
Reduced effectiveness of the sildenafil
Significant increase in pulse rate
Increased risk of bleeding
Significant decrease in blood pressure
The Correct Answer is D
Choice A reason: This is incorrect because sildenafil and nitrates do not affect each other's effectiveness, but rather their side effects. Sildenafil is a phosphodiesterase-5 inhibitor that enhances the effect of nitric oxide, which causes vasodilation and increases blood flow to the penis. Nitrates are vasodilators that also increase nitric oxide levels and reduce the workload of the heart.
Choice B reason: This is incorrect because sildenafil and nitrates do not cause a significant increase in pulse rate, but rather a decrease. This is because the vasodilation caused by both drugs lowers the blood pressure and the cardiac output, which reduces the heart rate.
Choice C reason: This is incorrect because sildenafil and nitrates do not increase the risk of bleeding, unless they are combined with other drugs that affect the blood clotting process, such as anticoagulants or antiplatelets.
Choice D reason: This is correct because sildenafil and nitrates can cause a significant decrease in blood pressure when taken together, as they both cause vasodilation and increase nitric oxide levels. This can lead to hypotension, dizziness, fainting, or even a heart attack or stroke. The patient should avoid taking sildenafil and nitrates within 24 hours of each other.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Decreases inflammation is a therapeutic effect of prednisone. Prednisone is a corticosteroid that suppresses the immune system and reduces the production of inflammatory mediators. This helps to relieve the pain, swelling, and stiffness of rheumatoid arthritis.
Choice B reason: Increases bone density is not a therapeutic effect of prednisone. Prednisone can cause bone loss and osteoporosis by decreasing calcium absorption and increasing calcium excretion. This increases the risk of fractures and bone damage.
Choice C reason: Reduces risk of infection is not a therapeutic effect of prednisone. Prednisone can increase the risk of infection by weakening the immune system and making it less able to fight off pathogens. This requires close monitoring and prophylactic antibiotics.
Choice D reason: Improves peripheral blood flow is not a therapeutic effect of prednisone. Prednisone can impair peripheral blood flow by causing vasoconstriction and increasing blood pressure. This can worsen the symptoms of peripheral vascular disease and increase the risk of thrombosis.
Correct Answer is B
Explanation
Choice A reason: The client waits 10 min between inhalations is not the correct answer. This is not a recommended practice for using an albuterol inhaler. The client should wait at least 1 min between inhalations to allow the medication to reach the lungs and avoid overdose.
Choice B reason: The client takes a quick inhalation while releasing the medication from the inhaler is the correct answer. This is the correct way to use an albuterol inhaler. The client should breathe in quickly and deeply while pressing down on the inhaler to release the medication. This ensures that the medication is delivered to the airways and not the mouth or throat.
Choice C reason: The client exhales as the medication is released from the inhaler is not the correct answer. This is not a recommended practice for using an albuterol inhaler. The client should exhale before using the inhaler, not during or after. Exhaling while using the inhaler can cause the medication to be wasted or to irritate the mouth or throat.
Choice D reason: The client holds his breath for 10 seconds after inhaling the medication is not the correct answer. This is not a recommended practice for using an albuterol inhaler. The client should hold his breath for only a few seconds after inhaling the medication, not 10 seconds. Holding the breath for too long can cause dizziness, headache, or chest discomfort.
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