A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil. He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?
Reduced effectiveness of the sildenafil
Significant increase in pulse rate
Increased risk of bleeding
Significant decrease in blood pressure
The Correct Answer is D
Choice A reason: This is incorrect because sildenafil and nitrates do not affect each other's effectiveness, but rather their side effects. Sildenafil is a phosphodiesterase-5 inhibitor that enhances the effect of nitric oxide, which causes vasodilation and increases blood flow to the penis. Nitrates are vasodilators that also increase nitric oxide levels and reduce the workload of the heart.
Choice B reason: This is incorrect because sildenafil and nitrates do not cause a significant increase in pulse rate, but rather a decrease. This is because the vasodilation caused by both drugs lowers the blood pressure and the cardiac output, which reduces the heart rate.
Choice C reason: This is incorrect because sildenafil and nitrates do not increase the risk of bleeding, unless they are combined with other drugs that affect the blood clotting process, such as anticoagulants or antiplatelets.
Choice D reason: This is correct because sildenafil and nitrates can cause a significant decrease in blood pressure when taken together, as they both cause vasodilation and increase nitric oxide levels. This can lead to hypotension, dizziness, fainting, or even a heart attack or stroke. The patient should avoid taking sildenafil and nitrates within 24 hours of each other.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: This is incorrect because insulin glargine has a longer duration than 6 to 10 hr. Insulin glargine is a long-acting insulin that provides a steady and continuous level of insulin in the blood. It is usually given once daily at the same time.
Choice B reason: This is incorrect because insulin glargine has a longer duration than 3 to 6 hr. Insulin glargine is not a short-acting or rapid-acting insulin that peaks quickly and lasts for a few hours. It is a long-acting insulin that does not have a peak and lasts for up to 24 hr.
Choice C reason: This is incorrect because insulin glargine has a longer duration than 16 to 24 hr. Insulin glargine is a long-acting insulin that can last for up to 24 hr, but not more than that. It is not an ultra-long-acting insulin that can last for more than 24 hr.
Choice D reason: This is correct because insulin glargine has a duration of 18 to 24 hr. Insulin glargine is a long-acting insulin that provides a steady and continuous level of insulin in the blood. It is usually given once daily at the same time.
Correct Answer is A
Explanation
Choice A reason: Hypokalemia is a low level of potassium in the blood. Furosemide is a loop diuretic that increases the excretion of water and electrolytes, including potassium. Hypokalemia can cause muscle weakness, cramps, arrhythmias, and digoxin toxicity.
Choice B reason: Hypoglycemia is a low level of glucose in the blood. Furosemide does not affect blood glucose levels or insulin secretion. Hypoglycemia may be caused by other factors such as diabetes medications, fasting, or alcohol intake.
Choice C reason: Weight gain is not an adverse effect of furosemide. Furosemide causes weight loss by reducing fluid retention and edema. Weight gain may be a sign of worsening heart failure or fluid overload.
Choice D reason: Increased blood pressure is not an adverse effect of furosemide. Furosemide lowers blood pressure by decreasing blood volume and cardiac preload. Increased blood pressure may be caused by other factors such as salt intake, stress, or kidney disease.
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