A 73-year-old male patient is in the clinic for a yearly physical and is asking for a prescription for sildenafil. He has listed on his health history that he is taking a nitrate for angina. The nurse is aware that which problem may occur if sildenafil is taken with a nitrate?
Reduced effectiveness of the sildenafil
Significant increase in pulse rate
Increased risk of bleeding
Significant decrease in blood pressure
The Correct Answer is D
Choice A reason: This is incorrect because sildenafil and nitrates do not affect each other's effectiveness, but rather their side effects. Sildenafil is a phosphodiesterase-5 inhibitor that enhances the effect of nitric oxide, which causes vasodilation and increases blood flow to the penis. Nitrates are vasodilators that also increase nitric oxide levels and reduce the workload of the heart.
Choice B reason: This is incorrect because sildenafil and nitrates do not cause a significant increase in pulse rate, but rather a decrease. This is because the vasodilation caused by both drugs lowers the blood pressure and the cardiac output, which reduces the heart rate.
Choice C reason: This is incorrect because sildenafil and nitrates do not increase the risk of bleeding, unless they are combined with other drugs that affect the blood clotting process, such as anticoagulants or antiplatelets.
Choice D reason: This is correct because sildenafil and nitrates can cause a significant decrease in blood pressure when taken together, as they both cause vasodilation and increase nitric oxide levels. This can lead to hypotension, dizziness, fainting, or even a heart attack or stroke. The patient should avoid taking sildenafil and nitrates within 24 hours of each other.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: 0.2 tablets is not the correct answer. To convert mg to mcg, multiply by 1000. Therefore, 0.175 mg is equal to 175 mcg. To find the number of tablets, divide the dose by the amount available. Therefore, 175 mcg / 8 mcg = 21.875 tablets. Round this to the nearest whole number, which is 22 tablets.
Choice B reason: 2 tablets is not the correct answer. This is the result of dividing the dose by 100 instead of 1000, which is incorrect.
Choice C reason: 20 tablets is not the correct answer. This is the result of rounding down instead of up, which is incorrect.
Choice D reason: 22 tablets is the correct answer. This is the result of converting the dose to mcg, dividing by the amount available, and rounding to the nearest whole number.
Correct Answer is A
Explanation
Choice A reason: This is correct because medroxyprogesterone is available as a depot injection that is given intramuscularly every three months. This provides a long-acting and effective contraception for women who do not want to take oral pills or use other methods.
Choice B reason: This is incorrect because medroxyprogesterone is not available as a vaginal form. However, there are other contraceptive options that can be inserted vaginally, such as rings, diaphragms, or caps.
Choice C reason: This is incorrect because medroxyprogesterone is not available as a transdermal form. However, there are other contraceptive options that can be applied to the skin, such as patches.
Choice D reason: This is incorrect because medroxyprogesterone is not available as a subcutaneous form. However, there are other contraceptive options that can be injected under the skin, such as implants.
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