A nurse is providing care for an older adult client who has hyperosmolar hyperglycemic syndrome (HHS). Which of the following clinical manifestations support the diagnosis? Select all that apply.
Acetone breath
Fever
68 years of age
Serum glucose 800 mg/dL (74 to 106 mg/dL)
Serum bicarbonate 15 mEq/L (21 to 28 mEq/L)
Insidious onset
Correct Answer : B,D,E,F
Choice A reason: Acetone Breath
Acetone breath is typically associated with diabetic ketoacidosis (DKA), not hyperosmolar hyperglycemic syndrome (HHS). In DKA, the body produces high levels of ketones, leading to a fruity or acetone-like breath odor. HHS, on the other hand, does not usually involve significant ketone production, so acetone breath is not a characteristic feature of HHS.
Choice B reason: Fever
Fever can be a clinical manifestation of HHS, often indicating an underlying infection, which is a common precipitating factor for HHS. Infections can exacerbate hyperglycemia and contribute to the development of HHS, making fever a relevant symptom to consider.
Choice C reason: 68 Years of Age
While age itself is not a clinical manifestation, HHS predominantly affects older adults, particularly those with type 2 diabetes. Therefore, being 68 years old is consistent with the typical demographic affected by HHS, but it is not a direct clinical manifestation.
Choice D reason: Serum Glucose 800 mg/dL
A serum glucose level of 800 mg/dL is significantly elevated and is a hallmark of HHS2. Normal serum glucose levels range from 74 to 106 mg/dL. Such high levels of glucose are indicative of severe hyperglycemia, which is a defining characteristic of HHS.
Choice E reason: Serum Bicarbonate 15 mEq/L
A serum bicarbonate level of 15 mEq/L is below the normal range of 21 to 28 mEq/L. This indicates metabolic acidosis, which can occur in HHS due to severe dehydration and impaired renal function. Although metabolic acidosis is more pronounced in DKA, it can still be present in HHS.
Choice F reason: Insidious Onset
HHS typically has an insidious onset, developing slowly over days to weeks. This gradual progression contrasts with the rapid onset of DKA and is a key feature in the clinical presentation of HHS.
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Correct Answer is B
Explanation
Choice A Reason:
Monitoring blood glucose levels is crucial for managing diabetes, but in the context of hyperosmolar hyperglycemic syndrome (HHS), recognizing the signs and symptoms is more critical. HHS is a serious condition characterized by extremely high blood sugar levels without significant ketoacidosis. Early recognition of symptoms such as extreme thirst, frequent urination, confusion, and weakness can prevent complications and prompt timely medical intervention.
Choice B Reason:
Recognizing signs and symptoms of HHS is the most important topic to prioritize. HHS can develop gradually and may be life-threatening if not identified and treated promptly. Patients and caregivers need to be aware of the warning signs to seek immediate medical attention. Symptoms include severe dehydration, altered mental status, and very high blood glucose levels. Educating patients on these signs ensures they can act quickly to prevent severe outcomes.
Choice C Reason:
Administering insulin correctly is essential for managing diabetes, but it is not the top priority in the context of HHS education. While proper insulin administration helps control blood glucose levels, the immediate concern in HHS is recognizing the condition’s onset. Once HHS is identified, insulin administration becomes part of the treatment plan, but early detection is key to preventing severe complications.
Choice D Reason:
Understanding the importance of hydration is important because dehydration is a significant component of HHS. Patients with HHS often experience severe dehydration due to high blood glucose levels leading to osmotic diuresis. Educating patients on maintaining adequate hydration can help manage their condition and prevent the onset of HHS. However, recognizing the symptoms of HHS remains the top priority.
Choice E Reason:
Managing diet and nutrition is a fundamental aspect of diabetes care, but it is not the primary focus when dealing with HHS. While a balanced diet helps maintain stable blood glucose levels, the immediate concern in HHS is identifying and responding to the condition’s symptoms. Once HHS is recognized and treated, dietary management becomes part of the long-term care plan.
Correct Answer is B
Explanation
Choice A Reason:
Conivaptan hydrochloride is a vasopressin receptor antagonist used to treat hyponatremia in patients with SIADH. It works by blocking the action of vasopressin, thereby promoting water excretion without significant loss of sodium. This helps to correct the water imbalance caused by SIADH. Conivaptan is typically administered intravenously and is effective in increasing serum sodium levels.
Choice B Reason:
Vasopressin, also known as antidiuretic hormone (ADH), is contraindicated in patients with SIADH because it exacerbates the condition. SIADH is characterized by excessive release of ADH, leading to water retention and hyponatremia. Administering vasopressin would further increase water reabsorption in the kidneys, worsening the hyponatremia.
Choice C Reason:
Sodium chloride tablets are used to manage hyponatremia in SIADH by increasing sodium intake. This helps to counteract the dilutional hyponatremia caused by excessive water retention. Sodium chloride tablets are often prescribed alongside fluid restriction to help raise serum sodium levels.
Choice D Reason:
Tolvaptan is another vasopressin receptor antagonist used to treat hyponatremia in SIADH. It works similarly to conivaptan by blocking the action of vasopressin, promoting water excretion, and increasing serum sodium levels. Tolvaptan is typically administered orally and is effective in managing SIADH.
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