A woman with severe preeclampsia is being treated with bed rest and intravenous magnesium sulfate. The drug classification of this medication is

Choice A) Increased urinary output: This is not a sign of sepsis in newborns. In fact, sepsis can cause reduced urinary output due to poor blood flow to the kidneys and dehydration.

Choice B) Hypothermia: This is a sign of sepsis in newborns. Sepsis can cause changes in temperature, often fever, but sometimes low temperature. Hypothermia can indicate a severe infection that affects the body's ability to regulate its temperature.

Choice C) Wakefulness: This is not a sign of sepsis in newborns. Sepsis can cause reduced activity and lethargy due to inflammation and organ dysfunction.

Choice D) Interest in feeding: This is not a sign of sepsis in newborns. Sepsis can cause reduced sucking and difficulty feeding due to poor appetite, nausea, vomiting, and abdominal distension.

Choice A) Decreased metabolic rate is incorrect because this is not a result of hypothermia in the newborn, but rather a cause of it. Metabolic rate is the speed at which the body uses energy to perform its functions. Newborns have a high metabolic rate, which helps them to maintain a normal body temperature of 36.5°C to 37.5°C (97.7°F to 99.5°F). However, some factors can lower the metabolic rate of newborns, such as prematurity, low birth weight, infection, or hypoglycemia. A low metabolic rate can make the newborn more susceptible to heat loss and hypothermia, which is a condition that occurs when the body temperature drops below 36°C (96.8°F). Therefore, this response is inaccurate and misleading.

Choice B) Decreased oxygen demands is incorrect because this is not a result of hypothermia in the newborn, but rather a consequence of it. Oxygen demand is the amount of oxygen that the body needs to function properly.

Newborns have a high oxygen demand, which helps them to support their growth and development. However, some factors can decrease the oxygen demand of newborns, such as hypothermia, sedation, or asphyxia. A low oxygen demand can impair the oxygen delivery and utilization by the tissues and organs, leading to hypoxia, acidosis, or organ failure. Therefore, this response is irrelevant and inaccurate.

Choice C) Shivering to generate heat is incorrect because this is not a result of hypothermia in the newborn, but rather a mechanism that is absent in them. Shivering is an involuntary contraction of the muscles that produces heat and raises the body temperature. It is a common response to cold exposure in adults and older children, but not in newborns. Newborns do not have the ability to shiver, as their muscles are immature and lack glycogen stores.

Instead, they rely on other methods to generate heat, such as non-shivering thermogenesis, which involves burning brown fat in certain areas of the body. Therefore, this response is irrelevant and inaccurate.

Choice D) Increased glucose demands is correct because this is a result of hypothermia in the newborn that can cause complications. Glucose demand is the amount of glucose that the body needs to produce energy and maintain its functions. Newborns have a high glucose demand, which helps them to support their metabolic rate and thermoregulation. However, some factors can increase the glucose demand of newborns, such as hypothermia, stress, or infection. A high glucose demand can deplete the glucose stores and cause hypoglycemia, which is a low level of glucose in the blood that can lead to seizures, brain damage, or death. Therefore, this response is clear and accurate.