A pregnant patient asks the nurse if she can take antihistamines for seasonal allergies during her pregnancy. What will the nurse tell the patient?

Acetaminophen is generally considered safe and well-tolerated when used appropriately. However, it is primarily metabolized by the liver, and in cases of severe hepatic impairment or liver failure, the metabolism of acetaminophen can be significantly impaired. This can lead to the accumulation of toxic metabolites, which can cause further liver damage and potentially result in hepatotoxicity.

Hypertension, gallbladder disease, and tachyarrhythmias are not typically considered contraindications for the use of acetaminophen. However, it is important to consider any potential interactions or precautions when using acetaminophen in patients with these conditions, and consulting with a healthcare provider is recommended to ensure the safe and appropriate use of the medication.

Rebound congestion, also known as rhinitis medicamentosa, is a common adverse effect associated with the prolonged use of nasal decongestants. It occurs when the blood vessels in the nasal passages become dependent on the medication for constriction and lose their ability to regulate naturally. As a result, when the medication wears off, the nasal congestion worsens, leading to a cycle of continued use and worsening symptoms.

In this scenario, the patient's complaint of worsening nasal congestion despite using oxymetazoline every 2 to 4 hours for the past 5 days suggests the possibility of rebound congestion. The nurse should explain to the patient that prolonged or frequent use of nasal decongestants can lead to this effect and recommend gradually tapering off the medication use or discontinuing it altogether. The nurse may also suggest alternative non-medication strategies for managing nasal congestion, such as saline nasal sprays or steam inhalation.