A patient has started taking clopidogrel (Plavix) after experiencing a transient ischemic attack. What adverse effects are associated with this drug? (Select all that apply)
Constipation
Bruising
Rash
Headache
Diarrhea
Correct Answer : B,C
A. Constipation: Constipation is not a commonly reported adverse effect of clopidogrel (Plavix). Clopidogrel is an antiplatelet medication that works by inhibiting platelet aggregation, and gastrointestinal effects such as constipation are not typically associated with its use.
B. Bruising: This is a correct answer. Bruising is a known adverse effect of clopidogrel. As an antiplatelet medication, clopidogrel inhibits platelet aggregation, which can increase the risk of bleeding and bruising.
C. Rash: Rash is a potential adverse effect of clopidogrel, although it is not as common as other side effects such as bruising or gastrointestinal symptoms. Patients taking clopidogrel should be monitored for signs of allergic reactions, including rash, which may indicate the need for further evaluation or discontinuation of the medication.
D. Headache: Headache is not a commonly reported adverse effect of clopidogrel. While some patients may experience headache while taking clopidogrel, it is not considered a frequent or significant side effect of the medication.
E. Diarrhea: Diarrhea is not a commonly reported adverse effect of clopidogrel. Gastrointestinal symptoms such as diarrhea are not typically associated with clopidogrel use, although some patients may experience gastrointestinal upset as a side effect of antiplatelet therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A. Clotting at the incision site. Enoxaparin (Lovenox) is an anticoagulant medication used to prevent blood clots, particularly deep vein thrombosis (DVT) and pulmonary embolism (PE), which are common complications following orthopedic surgeries like knee replacement. Monitoring for clotting at the incision site is essential to ensure that the medication is effectively preventing excessive clot formation while also ensuring that the patient does not experience excessive bleeding.
B. Increased pain. While increased pain could be a concern postoperatively, particularly after a surgical procedure like knee replacement, it is not a specific monitoring parameter for enoxaparin administration. Pain management is typically addressed separately, and increased pain may indicate issues such as inadequate analgesia, surgical complications, or other factors unrelated to enoxaparin therapy.
C. Gingival hyperplasia. Gingival hyperplasia refers to an overgrowth of gum tissue and is not directly associated with enoxaparin therapy. This side effect is more commonly associated with certain medications such as phenytoin and cyclosporine rather than anticoagulants like enoxaparin. Monitoring for gingival hyperplasia would not be relevant in this context.
D. Signs and symptoms of bruising and bleeding. This is the correct answer. Enoxaparin is an anticoagulant medication, which increases the risk of bleeding. Therefore, monitoring for signs and symptoms of bruising and bleeding is crucial to detect any potential complications such as hemorrhage or hematoma formation. This includes assessing for unusual bruising, bleeding from the gums, nosebleeds, hematuria, melena, or any other signs of internal or external bleeding. Prompt recognition and management of bleeding complications are essential to ensure patient safety during enoxaparin therapy, especially following orthopedic surgery.
Correct Answer is D
Explanation
A. Trombin (Evithrom): Incorrect: Thrombin (also known as factor IIa) is not typically used as a hemostatic drug. It is involved in the final step of the coagulation cascade, converting fibrinogen to fibrin to form a stable clot. However, it is not administered directly as a medication.
B. Aminocaproic acid (Amicar): Aminocaproic acid is an antifibrinolytic agent commonly used to control bleeding. It works by inhibiting the breakdown of fibrin clots, thus promoting hemostasis. It is particularly useful in situations where excessive bleeding occurs due to impaired clot dissolution. However, tranexamic acid is generally considered more potent and has a longer-lasting effect, making it the preferred choice in many situations.
C. Aspirin: Incorrect: Aspirin is an antiplatelet medication that inhibits platelet aggregation. While it can reduce the risk of clot formation, it is not primarily used for controlling postoperative bleeding.
D. Tranexamic acid (Cyklokapron): Correct: Tranexamic acid is another antifibrinolytic agent that helps prevent excessive bleeding. It works by blocking the breakdown of fibrin clots. Tranexamic acid is commonly used in surgical settings to manage bleeding during and after procedures.
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