What is the primary advantage of using low molecular weight heparins (LMWHs) over heparin?

LMWHs produce a more stable effect on coagulation; thus, fewer lab tests are needed.

LMWHs may be given by the oral route

LMWHs have a short duration of action

LMWHs possess greater anticoagulant activity

Answer and Explanation

The Correct Answer is A

A. LMWHs produce a more stable effect on coagulation; thus, fewer lab tests are needed: Correct LMWHs have a more predictable anticoagulant response compared to unfractionated heparin, resulting in a more stable effect on coagulation. Because of their predictable response, routine monitoring of coagulation parameters, such as activated partial thromboplastin time (aPTT), is typically not required with LMWH therapy, unlike with unfractionated heparin.

B. LMWHs may be given by the oral route: Incorrect. LMWHs are administered by the subcutaneous route.

C. LMWHs have a short duration of action: Incorrect. LMWHs have a longer duration of action compared to unfractionated heparin.

D. LMWHs possess greater anticoagulant activity: incorrect. LMWHs generally have less potent anticoagulant activity compared to unfractionated heparin, but their more predictable response and longer half-life make them advantageous in many clinical scenario

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Correct Answer is D

Explanation

A. Diminished effect from warfarin: This is unlikely because displacement of warfarin from protein binding sites would increase its concentration in the bloodstream, potentially leading to increased anticoagulant effects and toxicity.

B. Diminished effect from paroxetine: This is also unlikely because displacement of paroxetine from protein binding sites would increase its concentration in the bloodstream, potentially leading to increased pharmacological effects and toxicity.

C. Increased effect, and toxicity from paroxetine: If paroxetine displaces warfarin from protein binding sites, it can increase the concentration of free warfarin in the bloodstream, leading to increased anticoagulant effects and potential toxicity.

D. Increased effect, and toxicity from warfarin: Correct. If warfarin is displaced from protein binding sites by paroxetine, it can increase the concentration of free warfarin in the bloodstream, leading to increased anticoagulant effects and potential toxicity.

Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"A"}

Explanation

a. Hemostasis: Hemostasis refers to the process of stopping bleeding or preventing excessive blood loss. It involves several steps, including vasoconstriction, platelet aggregation, and clot formation. Hemostasis is the correct answer because it directly addresses the stopping of blood flow to protect the body from injury.

b. Thrombolytics: Thrombolytics are medications used to dissolve blood clots. They are not the natural mechanism for stopping blood flow. Thrombolytics are not the correct answer in this context.

c. Hematopoiesis: Hematopoiesis is the process of forming blood cells (including red blood cells, white blood cells, and platelets) in the bone marrow. It is essential for maintaining blood cell populations but does not directly stop blood flow. Hematopoiesis is not related to stopping blood flow.

d. Anticoagulation: Anticoagulation refers to preventing blood clot formation. While it is important for certain medical conditions, it does not directly stop blood flow. Anticoagulation is not the primary mechanism for stopping bleeding.

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What is the primary advantage of using low molecular weight heparins (LMWHs) over heparin?

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Naxlex Comprehensive Predictor Exams

Correct Answer is D

Explanation

is the stopping of blood flow, an essential mechanism protecting the body from both external and internal injury.

Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"A"}

Explanation

Which of the following clump and adhere to the wall of the injured blood vessel to begin the process of hemostasis?

Unlike heparin, the anticoagulant activity of warfarin can take several to reach its maximum effect.

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What is the primary advantage of using low molecular weight heparins (LMWHs) over heparin?