A patient has been taking ergotamine to relieve their migraines. Which of the following adverse effects would indicate to the nurse that the drug may have entered into toxic levels?

Diarrhea

Delirium

Hypotension

Bradycardia

Answer and Explanation

The Correct Answer is B

A.   Diarrhea is not typically associated with ergotamine toxicity. Gastrointestinal symptoms such as nausea and vomiting are more common adverse effects of ergotamine use.
B.   Delirium is a potential sign of ergotamine toxicity. At toxic levels, ergotamine can cause central nervous system symptoms such as confusion, hallucinations, and delirium.
C.   Hypotension may occur as an adverse effect of ergotamine due to its vasoconstrictive properties. However, hypotension alone may not indicate ergotamine toxicity.
D.   Bradycardia is not a typical adverse effect of ergotamine. Ergotamine is more commonly associated with vasoconstriction and can lead to hypertension or tachycardia rather than bradycardia.

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Correct Answer is B

Explanation

A. Decreased urine output is not the primary intended effect of an adrenergic agonist in the

treatment of shock. While adrenergic agonists may increase blood pressure, leading to a decrease in urine output due to vasoconstriction, the primary goal of administering these drugs in shock is to improve tissue perfusion and cardiac output.
B. Increased cardiac output is the primary intended effect of adrenergic agonists in the treatment of shock. These medications stimulate adrenergic receptors, leading to increased heart rate, contractility, and stroke volume, ultimately improving cardiac output and tissue perfusion.
C. Volume restoration may be a secondary effect of administering fluids along with adrenergic agonists in the treatment of shock, but it is not the primary intended effect of the medication
itself.

D. Reduced anxiety is not a primary goal of administering adrenergic agonists in the treatment of shock. While these medications may have anxiolytic effects in certain situations, the primary goal is to improve cardiovascular function and tissue perfusion.

A. Carbidopa prevents the breakdown of levodopa in the periphery. B. Carbidopa is the biologic precursor of dopamine and can penetrate into the central nervous system. C. Carbidopa allows for larger doses of levodopa to be given. D. There are concerns about drug-food interactions with levodopa therapy that do not exist with the combination therapy.

Correct Answer is A

Explanation

A. Carbidopa prevents the breakdown of levodopa in the periphery, specifically in the gastrointestinal tract and peripheral tissues, allowing more levodopa to reach the brain and be converted to dopamine. This enhances the effectiveness of levodopa therapy in managing the symptoms of Parkinson's disease.
B. Carbidopa is not the biologic precursor of dopamine. It is a peripheral decarboxylase inhibitor that does not cross the blood-brain barrier.
C. Carbidopa does not directly allow for larger doses of levodopa to be given. However, by

inhibiting the peripheral breakdown of levodopa, it enhances the availability of levodopa to the central nervous system, potentially improving therapeutic efficacy.
D. While levodopa-carbidopa combination therapy may have fewer drug-food interactions compared to levodopa alone, the primary reason for combining these medications is to enhance the effectiveness of levodopa by preventing its peripheral breakdown.

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A patient has been taking ergotamine to relieve their migraines. Which of the following adverse effects would indicate to the nurse that the drug may have entered into toxic levels?

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Naxlex Comprehensive Predictor Exams

An adrenergic agonist is ordered for a patient in shock. The nurse will note that this drug has had its primary intended effect if which expected outcome occurs?

Correct Answer is B

Explanation

A patient has been given a prescription for levodopa-carbidopa for a new diagnosis of Parkinson's disease. The patient asks the nurse, "Why are there two drugs in this pill?" The nurse's best response reflects which fact?

Correct Answer is A

Explanation

When a patient is taking an anticholinergic such as benztropine as part of the treatment for Parkinson's disease, the nurse should include which information in the teaching plan?

A patient has been treated with antiparkinson medications for 3 months. What therapeutic responses should the nurse look for when assessing this patient?

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