A nurse is working with a woman who has been diagnosed with severe fibrocystic breast disease. After describing the medications that can be used as treatment, the nurse determines that additional teaching is needed when the client identifies which drug is being used.

Choice A: Growth spurt is not the correct answer because it is not the first event that occurs in female puberty. The growth spurt is a period of rapid increase in height and weight that usually occurs between 10 and 14 years of age in girls. It is influenced by various factors such as genetics, nutrition, and hormones. Growth spurt usually follows the development of breast buds and pubic hair by about 6 to 12 months.

Choice B: Evidence of pubic hair is not the correct answer because it is not the first event that occurs in female puberty. Evidence of pubic hair is the appearance of coarse, curly, and pigmented hair on the pubic area and around the genitals. It usually occurs between 8 and 13 years of age in girls. It is caused by the increased production of androgens (male hormones) by the adrenal glands and ovaries. Evidence of pubic hair usually follows the development of breast buds by about 3 to 6 months.

Choice C: Onset of menses is not the correct answer because it is not the first event that occurs in female puberty. The onset of menses is the beginning of menstrual cycles, which are regular changes in the female reproductive system that prepare the body for pregnancy. It usually occurs between 10 and 15 years of age in girls. It is caused by the maturation of the hypothalamus, pituitary gland, ovaries, and uterus, which regulate the levels of estrogen and progesterone (female hormones). The onset of menses usually follows the development of breast buds and pubic hair by about 2 to 3 years.

Choice D: Development of breast buds is the correct answer because it is the first event that occurs in female puberty. Development of breast buds is the enlargement and elevation of the nipples and areolas (dark circles around the nipples), which indicate the beginning of breast growth. It usually occurs between 8 and 12 years of age in girls. It is caused by the increased production of estrogen (female hormone) by the ovaries, which stimulates the growth of ducts (tubes) and lobules (glands) in the breast tissue. The development of breast buds is also called thelarche or breast stage 2.

Choice A: Danazol is not the correct answer because it is a drug that can be used to treat fibrocystic breast disease. Danazol is a synthetic hormone that reduces the production of estrogen and progesterone, which are involved in the development of breast cysts.

Choice B: Penicillin is the correct answer because it is a drug that has no effect on fibrocystic breast disease. Penicillin is an antibiotic that is used to treat bacterial infections, such as strep throat or syphilis. It has no role in the management of fibrocystic breast disease.

Choice C: Bromocriptine is not the correct answer because it is a drug that can be used to treat fibrocystic breast disease. Bromocriptine is a dopamine agonist that inhibits the secretion of prolactin, which is a hormone that stimulates breast tissue growth and milk production.

Choice D: Tamoxifen is not the correct answer because it is a drug that can be used to treat fibrocystic breast disease. Tamoxifen is an anti-estrogen that blocks the action of estrogen on breast cells, which can reduce the size and number of breast cysts.