A nurse is reviewing the medical history of a client who is to start taking prednisone. Which of the following findings should the nurse identify as a contraindication to prednisone therapy?

Prior episode of kidney stones

Taking levothyroxine orally

Has a systemic fungal infection

History of asthma

Answer and Explanation

The Correct Answer is C

A.   Prior episode of kidney stones: A history of kidney stones is not a contraindication to prednisone therapy. However, it may require monitoring due to potential fluid and electrolyte imbalances associated with corticosteroid use.
B.   Taking levothyroxine orally: Taking levothyroxine orally is not a contraindication to prednisone therapy. However, concurrent use of corticosteroids and levothyroxine may require dosage adjustments of both medications due to potential interactions.
C.   Has a systemic fungal infection: Corticosteroids like prednisone can suppress the immune system, increasing the risk of fungal infections and worsening existing fungal infections.
Therefore, the presence of a systemic fungal infection is a contraindication to corticosteroid therapy.
D.   History of asthma: Asthma is not a contraindication to prednisone therapy. In fact, prednisone is commonly used as a treatment for asthma exacerbations. However, caution may be needed in individuals with asthma to avoid exacerbating symptoms or complications.

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Correct Answer is C

Explanation

A. Amphotericin B lipid complex naturally appears as an opaque, yellow to amber colored suspension. Discarding the medication because it is yellow is incorrect, as this is its expected normal appearance.

B. Amphotericin B lipid complex is highly incompatible with saline solutions and will precipitate if it comes into contact with them. The IV tubing must be primed and flushed strictly with 5% Dextrose in Water (D5W), not 0.9% sodium chloride.

C. The standard recommended administration protocol for amphotericin B lipid complex is to deliver the intravenous infusion at a rate of 2.5 mg/kg/hour, which typically translates to an overall infusion duration of approximately 2 hours.

D. To avoid accidental rapid infusion, which can induce severe adverse effects such as acute hypotension, cardiac arrhythmias, and cardiopulmonary arrest, amphotericin B must always be regulated by an electronic infusion pump rather than a manual gravity flow set.

A. "You may crush the medication and mix it with applesauce." B. "You will need liver function tests before beginning therapy." C. "Avoid consuming dairy products while taking this medication." D. "You should take the medication in the morning."

Correct Answer is B

Explanation

A. "You may crush the medication and mix it with applesauce": Lovastatin extended-release tablets should not be crushed or chewed as it may alter the drug's release profile, leading to
potential adverse effects or reduced efficacy. Therefore, this statement is incorrect and should not be included in the teaching.
B. "You will need liver function tests before beginning therapy": Lovastatin is a statin

medication used to lower cholesterol levels. Liver function tests (LFTs) are necessary before starting statin therapy and periodically during treatment to monitor for potential hepatotoxicity.
C. "Avoid consuming dairy products while taking this medication": Lovastatin can be taken with or without food, and there is no specific requirement to avoid dairy products. This statement is not relevant to lovastatin therapy and should not be included in the teaching.
D. "You should take the medication in the morning": Lovastatin can be taken at any time of the day, with or without food. There is no specific requirement to take it in the morning. Therefore, this statement is incorrect and should not be included in the teaching.

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A nurse is reviewing the medical history of a client who is to start taking prednisone. Which of the following findings should the nurse identify as a contraindication to prednisone therapy?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is preparing to administer amphotericin B lipid complex via intermittent IV bolus to a client who has infective endocarditis. Which of the following actions should the nurse take?

Correct Answer is C

Explanation

A nurse is instructing a client who has a new prescription for a daily dose of lovastatin extended release. Which of the following information should the nurse include in the teaching?

Correct Answer is B

Explanation

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