A nurse is caring for a client who has major burns and is experiencing dehydration. The nurse should anticipate a prescription to infuse which of the following solutions?

A. Amphotericin B lipid complex naturally appears as an opaque, yellow to amber colored suspension. Discarding the medication because it is yellow is incorrect, as this is its expected normal appearance.

B. Amphotericin B lipid complex is highly incompatible with saline solutions and will precipitate if it comes into contact with them. The IV tubing must be primed and flushed strictly with 5% Dextrose in Water (D5W), not 0.9% sodium chloride.

C. The standard recommended administration protocol for amphotericin B lipid complex is to deliver the intravenous infusion at a rate of 2.5 mg/kg/hour, which typically translates to an overall infusion duration of approximately 2 hours.

D. To avoid accidental rapid infusion, which can induce severe adverse effects such as acute hypotension, cardiac arrhythmias, and cardiopulmonary arrest, amphotericin B must always be regulated by an electronic infusion pump rather than a manual gravity flow set.

A. 0.45% sodium chloride: 0.45% sodium chloride solution, also known as half-normal saline, is a hypotonic solution used for rehydration and maintenance fluid therapy. However, in cases of
major burns where there is a significant loss of fluid and electrolytes, isotonic solutions are generally preferred.
B. Lactated Ringer's: Lactated Ringer's solution is an isotonic crystalloid solution that closely resembles the electrolyte composition of extracellular fluid. It is commonly used for fluid resuscitation in clients with major burns to replace lost fluids and electrolytes and restore
intravascular volume.

C. Dextrose 5% in water: Dextrose 5% in water is a hypotonic solution used primarily for hydration in clients with normal electrolyte levels or as a vehicle for administering medications.
It is not typically used for fluid resuscitation in clients with major burns, as it does not adequately replace lost electrolytes.
D. Dextrose 5% in 0.45% sodium chloride: This solution combines dextrose 5% and 0.45% sodium chloride and is used for maintenance fluid therapy and mild dehydration. However, in cases of major burns where there is significant fluid and electrolyte loss, isotonic solutions like lactated Ringer's or normal saline are preferred for fluid resuscitation.