A nurse is reviewing the BUN result of a client who is taking cyclosporine following a kidney transplant. Which of the following laboratory studies should the nurse recognize as another renal function study that should be monitored?

Rationale for Correct Choices

• Reye's syndrome: The toddler presents with acute onset of vomiting, lethargy, and altered mental status following a recent viral illness (influenza A). These are hallmark signs of Reye’s syndrome, a rare but serious condition causing hepatic and cerebral dysfunction in children.

• Aspirin administration: Use of aspirin during viral infections in children is strongly associated with the development of Reye’s syndrome. The guardians reported alternating aspirin with acetaminophen, directly increasing the toddler’s risk for this potentially life-threatening condition.

Rationale for Incorrect Choices

• Gastroenteritis: Gastroenteritis typically presents with diarrhea, abdominal cramping, and vomiting. While vomiting is present, the toddler also demonstrates lethargy and neurologic changes, which are not characteristic of routine gastroenteritis.

• Bronchitis: Bronchitis usually causes productive cough, wheezing, or respiratory distress. This toddler has a non-productive cough and clear lung sounds, making bronchitis an unlikely explanation for the current acute neurological and systemic symptoms.

• Oseltamivir administration: Oseltamivir is an antiviral used to treat influenza and is not associated with the development of Reye’s syndrome. The toddler’s severe symptoms are unrelated to this medication.

• Acetaminophen administration: Acetaminophen is generally safe in children at recommended doses. While it can cause liver toxicity in overdose, the scenario indicates appropriate use, making it an unlikely contributor to the toddler’s presentation.

Rationale:
A. The client takes multiple steps while holding the walker: Taking several steps while holding the walker increases the risk of imbalance and falls. The correct technique is to move the walker forward one step length, ensure all four legs are stable on the ground, and then take a single step toward it before moving the other leg.

B. The client lifts the walker as it is moved forward: The walker should be lifted slightly and placed firmly on the ground to ensure stability with each step. Sliding the walker instead of lifting it can cause uneven movement or tipping, especially on rough surfaces, making lifting the correct method.

C. The client advances the walker and takes a step towards it: This is the proper technique for safe use. The client should advance the walker first, then step forward with the weaker leg, followed by the stronger leg, maintaining balance and even weight distribution.

D. The client grasps the walker by the hand grips on the upper bars: Proper hand placement on the upper hand grips ensures stability and correct posture during ambulation. Holding the walker anywhere else can cause poor control, imbalance, or wrist strain.