A nurse is reading a journal article about the care of a woman with pelvic organ prolapse. The nurse would expect to find information related to which disorder? Select all that apply.

Choice A: African American women have the BRCA 1 and BRCA 2 gene is not the correct answer because it is not a fact but a misconception. BRCA 1 and BRCA 2 are genes that normally help prevent breast and ovarian cancer by repairing DNA damage. However, mutations in these genes can increase the risk of developing these cancers. BRCA mutations are not exclusive to African American women, but they can affect any race or ethnicity. According to the National Cancer Institute, about 12% of American white women and 10% of African American women have a BRCA mutation.

Choice B: American white women respond better to breast cancer treatment is not the correct answer because it is not a fact but a disparity. Breast cancer treatment can include surgery, radiation, chemotherapy, hormone therapy, or targeted therapy. The response to treatment can vary depending on various factors such as tumor type, stage, grade, or molecular profile. However, some studies have shown that American white women have better survival rates and outcomes than African-American women after breast cancer treatment. This disparity may be due to differences in access to care, quality of care, socioeconomic status, or biological factors.

Choice C: Breast cancer is more advanced in African American women when found is the correct answer because it is a fact and a disparity. Breast cancer is a disease that occurs when abnormal cells grow and invade the breast tissue or other parts of the body. The stage of breast cancer describes how far the cancer has spread and how serious it is. Breast cancer can be detected by screening tests such as mammograms or clinical exams such as breast self-exams. However, some studies have shown that African American women are more likely than American white women to be diagnosed with breast cancer at later stages. This disparity may be due to differences in screening rates, awareness, symptoms, or tumor biology.

Choice D: More Hispanic women smoke, which increases their risk is not the correct answer because it is not a fact but a misconception. Smoking is a risk factor for breast cancer, as it can damage the DNA of breast cells and increase the levels of hormones that stimulate cell growth. However, smoking rates are not higher among Hispanic women than other racial or ethnic groups. According to the Centers for Disease Control and Prevention, about 14% of Hispanic women smoke cigarettes compared to 16% of American white women and 14% of African American women.

Choice A: Diarrhea is not the correct answer because it is not a common adverse effect of radiation treatment for breast cancer. Diarrhea is a condition that causes loose, watery, or frequent stools. It can be caused by various factors such as infection, medication, or food intolerance. It is more likely to occur as an adverse effect of radiation treatment for cancers that affect the digestive system, such as colorectal or stomach cancer.

Choice B: Anorexia is not the correct answer because it is not a common adverse effect of radiation treatment for breast cancer. Anorexia is a condition that causes loss of appetite or interest in food. It can be caused by various factors such as depression, stress, or nausea. It is more likely to occur as an adverse effect of chemotherapy or other systemic treatments for cancer that affect the whole body.

Choice C: Fatigue is the correct answer because it is a common adverse effect of radiation treatment for breast cancer. Fatigue is a condition that causes extreme tiredness or exhaustion that is not relieved by rest or sleep. It can be caused by various factors such as anemia, inflammation, or pain. It is a common adverse effect of radiation treatment for any type of cancer, as radiation can damage healthy cells and tissues and affect the body's energy production.

Choice D: Alopecia is not the correct answer because it is not a common adverse effect of radiation treatment for breast cancer. Alopecia is a condition that causes hair loss or thinning on the scalp or other parts of the body. It can be caused by various factors such as genetics, hormones, or infection. It is more likely to occur as an adverse effect of chemotherapy or other systemic treatments for cancer that affect the whole body.